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Influenza A virus Nucleoprotein antibody

Orthogonal
Anti-Influenza A virus Nucleoprotein antibody used in ELISA (ELISA). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in ELISA (ELISA). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in ELISA (ELISA). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in IHC (Paraffin sections) (IHC-P). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot and Immunoprecipitation (WB IP). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

Cat. No. GTX125989

Reference 123
3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP, ELISA, Sandwich ELISA

Reactivity

 Influenza A virus
Package
100 μl ($399),
25 μl ($169)
See all Influenza A virus Nucleoprotein products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:5000-1:20000
ICC/IF 1:100-1:1000
IHC-P Assay dependent
IP Assay dependent
ELISA Assay dependent
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture: GTX629633, Detection: GTX125989 or Capture: GTX125989, Detection: GTX629633
Not tested in other applications.

Positive Control

DF1 (Influenza A virus treatment for 10hr)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.15 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Influenza A virus

Immunogen

Recombinant protein of Influenza A virus Nucleoprotein (A/WSN/1933(H1N1). The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11168364

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Influenza A Virus Nucleoprotein , Influenza A Virus NP

Research Area

DATA IMAGES

Anti-Influenza A virus Nucleoprotein antibody used in ELISA (ELISA). GTX125989

GTX125989 ELISA Image

Sandwich ELISA detection of recombinant full-length Influenza A virus NP (nucleoprotein) protein, DDDDK tag (GTX135868-pro) using Influenza A virus NP (nucleoprotein) antibody [GT1236] (GTX629633) as capture antibody at concentration of 5 μg/mL and Influenza A virus NP (nucleoprotein) antibody (GTX125989) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in ELISA (ELISA). GTX125989

GTX125989 ELISA Image

Sandwich ELISA detection of non-transfected and Influenza A virus nucleoprotein transfected 293T whole cell extracts using Influenza A virus NP (nucleoprotein) antibody [GT1236] (GTX629633) as capture antibody at concentration of 5 μg/mL and Influenza A virus NP (nucleoprotein) antibody (GTX125989) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Non-infected (–) and infected (+) DF1 whole cell extracts (5 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Influenza A virus NP (nucleoprotein) antibody (GTX125989) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Influenza A viral lysate (1 ug & 1ng μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Influenza A virus NP (nucleoprotein) antibody (GTX125989) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in ELISA (ELISA). GTX125989

GTX125989 ELISA Image

Sandwich ELISA detection of recombinant full-length Influenza A virus NP (nucleoprotein) protein, DDDDK tag (GTX135868-pro) using Influenza A virus NP (nucleoprotein) antibody (GTX125989) as capture antibody at concentration of 5 μg/mL and Influenza A virus NP (nucleoprotein) antibody [GT1236] (GTX629633) as detection antibody at concentration of 1 μg/mL. Mouse IgG antibody (HRP) (GTX213111-01) was diluted at 1:10000 and used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Influenza A virus lysate (H1N1) infected 293T whole cell extract was separated by 12% SDS-PAGE, and the membrane was blotted with Influenza A virus NP (nucleoprotein) antibody (GTX125989) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989

GTX125989 ICC/IF Image

Orthogonal

Immunofluorescent analysis of Influenza virus infected cells using Influenza A virus Nucleoprotein antibody antibody (GTX125989).
Sample: Influenza A and B virus infected cells slide.
Green: Influenza A virus Nucleoprotein antibody antibody (GTX125989) diluted at 1:100.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Influenza A virus Nucleoprotein antibody (GTX125989) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Non-infected (–) and infected (+) H1299 whole cell extract (15 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Influenza A virus Nucleoprotein antibody (GTX125989) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Influenza A (H1N1) viral lysate (0.1 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with Influenza A virus Nucleoprotein antibody (GTX125989) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989

GTX125989 ICC/IF Image

Influenza A virus Nucleoprotein antibody detects Influenza A virus Nucleoprotein protein at cytoplasm by immunofluorescent analysis.
Sample: Mock and transfected 293T cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Influenza A virus Nucleoprotein stained by Influenza A virus Nucleoprotein antibody (GTX125989) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).
Scale bar= 10μm.

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Orthogonal

The data was published in the journal Oncotarget in 2018. PMID: 29492200

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Orthogonal

The data was published in the journal Front Immunol in 2017. PMID: 29312300

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Orthogonal

The data was published in the journal Front Immunol in 2017. PMID: 29312300

Anti-Influenza A virus Nucleoprotein antibody used in IHC (Paraffin sections) (IHC-P). GTX125989

GTX125989 IHC-P Image

Orthogonal

The data was published in the journal Virol J in 2020. PMID: 32321537

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Orthogonal

The data was published in the journal Virol J in 2020. PMID: 32321537

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Orthogonal

The data was published in the journal J Virol in 2018.PMID: 30209172

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

Orthogonal

The data was published in the journal J Virol in 2018.PMID: 30209172

Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989

GTX125989 ICC/IF Image

The data was published in the journal Front Immunol in 2017. PMID: 29312300

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot and Immunoprecipitation (WB IP). GTX125989

GTX125989 WB IP Image

The data was published in the journal Front Immunol in 2017. PMID: 29312300

Anti-Influenza A virus Nucleoprotein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX125989

GTX125989 ICC/IF Image

The data was published in the journal Front Immunol in 2017. PMID: 29312300

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal Front Immunol in 2017. PMID: 29312300

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal Front Immunol in 2018.PMID: 29904383

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal J Virol in 2018.PMID: 30209172

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal Front Immunol in 2018.PMID: 29904383

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal Sci Rep in 2015.PMID: 26030097

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal J Virol in 2018.PMID: 30209172

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal Front Immunol in 2018.PMID: 29904383

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the 2022 in Cell Death Discov. PMID: 35246529

Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989

GTX125989 WB Image

The data was published in the journal Sci Rep in 2017. PMID: 28842649

REFERENCE

Application Reference

Ouyang A et al. Adv Sci (Weinh) 2024; 11 (39) : e2404365 The Hemagglutinin of Influenza A Virus Induces Ferroptosis to Facilitate Viral Replication.
Hung CT et al. bioRxiv 2024; Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm.
Gabele L et al. Front Cell Neurosci 2024; 18 : 1444876 H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro.
D Hawman et al. Research Square 2024; Clade 2.3.4.4b but not historical clade 1 HA replicating RNA vaccine protects against bovine H5N1 challenge
X Li et al. Emerg Microbes Infect 2024; 13 (1) : 2387439 The PB2 I714S mutation influenced mammalian adaptation of the H3N2 canine influenza virus by interfering with nuclear import efficiency and RNP complex assembly
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REVIEW

Influenza A virus Nucleoprotein antibody Cat. No. GTX125989

Rating
( Average 5 based on 3 users reviews)
Application
Western Blot(WB)
( Average 5 based on 3 users reviews)
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Date : Chen-I Hsu submitted on 16-Sep-2021
Score :
Application Tested : WB
Sample Species : Influenza A virus
Sample : A549 cells
Amount used : 30μg
Blocking : 5% milk in TBST, 25°C, 1Hr
Primary Antibody : 1:2000, 4°C, 16Hr
Secondary Antibody : GTX213110-01, 1:2000, 25°C, 1Hr
Lane Description :
Left : A549 cells were transfected with pcDNA3-NP (WSN) using Lipofectamine3000. The cell was harvested at 24h post-transfection.
Right : A549 cells were infected with Influenza A (WSN) (MOI=0.1) and harvested at 6, 24, 48 hours postinfection.
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Date : Anonymous submitted on 14-May-2021
Score :
Application Tested : WB
Sample Species : Influenza A virus
Sample : A549 cells
Amount used : 5 μL
Blocking : 3% BSA in TBST, 4°C, 1Hr
Primary Antibody : 1:10000, 4°C, 16Hr
Anti-Influenza A virus Nucleoprotein antibody used in Western Blot (WB). GTX125989
Date : Anonymous submitted on 24-Jun-2015
Score :
Application Tested : WB
Sample Species : Influenza A virus
Sample : influenza virus (A/WSN/33) infected MDCK cells
Amount used : 3 x 10^3 cells
Blocking : 5% nonfat drymilk in TBST, 25°C, overnightHr
Primary Antibody : 1:30000, 25°C, 4Hr
Lane Description : Lane 1: influenza virus (A/WSN/33) infected MDCK cells (MOI=1 9hr). Lane 2: MDCK cells.
Submit a Review
Application Reference
Ouyang A et al. Adv Sci (Weinh) 2024; 11 (39):e2404365 The Hemagglutinin of Influenza A Virus Induces Ferroptosis to Facilitate Viral Replication.
Hung CT et al. bioRxiv 2024; Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm.
Gabele L et al. Front Cell Neurosci 2024; 18:1444876 H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro.
D Hawman et al. Research Square 2024; Clade 2.3.4.4b but not historical clade 1 HA replicating RNA vaccine protects against bovine H5N1 challenge
X Li et al. Emerg Microbes Infect 2024; 13 (1):2387439 The PB2 I714S mutation influenced mammalian adaptation of the H3N2 canine influenza virus by interfering with nuclear import efficiency and RNP complex assembly
L Cao et al. Emerg Microbes Infect 2024;:2387910 Inhibition of RAN Attenuates Influenza A Virus Replication and Nucleoprotein Nuclear Export
Lim CM et al. Heliyon 2024; 10 (12):e33049 Betacyanins from red pitahaya (Hylocereus polyrhizus) exhibit antiviral response against influenza A virus.
CM Lim et al. Heliyon 2024; Betacyanins from red pitahaya (Hylocereus polyrhizus) exhibit antiviral response against influenza A virus
YJ Li et al. PLoS Pathog 2024; 20 (5):e1012279 OTUB1 contributes to the stability and function of Influenza A virus NS2
Ciminski K et al. J Virol 2024; 98 (4):e0197223 Functionality of IAV packaging signals depends on site-specific charges within the viral nucleoprotein.
Halwe NJ et al. Nat Commun 2024; 15 (1):3450 Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets.
Y Sun et al. Research Square 2024; Influenza virus infection activates TAK1 to suppress RIPK3- independent apoptosis and RIPK1-dependent necroptosis
Y Li et al. Phytomed Plus 2024; 4 (2):100553 Cepharanthine inhibits influenza A virus replication by impairing viral polymerase activity and regulating influenza-induced immune response
Meng X et al. Virol Sin 2024; 39 (1):81-96 HIF-1α promotes virus replication and cytokine storm in H1N1 virus-induced severe pneumonia through cellular metabolic reprogramming.
WK Cho et al. J Funct ?Foods 2024; 112:105940 Hoveniae Semen Seu Fructus water extract inhibits influenza A virus infection
Application : ICC/IF
Ciacci Zanella G et al. Front Genome Ed 2023; 5:1320180 Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus.
Dong M et al. Virol Sin 2023; 38 (6):931-939 Allopregnanolone targets nucleoprotein as a novel influenza virus inhibitor.
Lamb CH et al. bioRxiv 2023; Cas13-based amplification-free quantification of aberrant RNAs during influenza virus infection.
Zou J et al. J Virol 2023; 97 (10):e0092623 Prohibitin1 facilitates viral replication by impairing the RIG-I-like receptor signaling pathway.
M He et al. Int Immunopharmacol 2023; Anti-influenza drug screening and inhibition of apigetrin on influenza A virus replication via TLR4 and autophagy pathways
Rigby CV et al. Virus Evol 2023; 9 (2):vead056 Evolution of?transient RNA structure-RNA polymerase interactions in?respiratory RNA virus genomes.
Resnick JD et al. bioRxiv 2023; Growth media affects susceptibility of air-lifted human nasal epithelial cell cultures to SARS-CoV2, but not Influenza A, virus infection.
Zhao Z et al. Viruses 2023; 15 (8) Host DNA Demethylation Induced by DNMT1 Inhibition Up-Regulates Antiviral OASL Protein during Influenza a Virus Infection.
Kleinehr J et al. PLoS Pathog 2023; 19 (7):e1010986 Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA.
Rigby C et al. bioRxiv 2023; Evolution of transient RNA structure-RNA polymerase interactions in respiratory RNA virus genomes.
D Luo et al. Virol Sin 2023; S1995-820X (23):00062-7 PA-E18G substitution in influenza A virus confers resistance to ZX-7101, a cap-dependent endonuclease inhibitor
Application : ICC/IF
Zhu Y et al. PLoS Pathog 2023; 19 (4):e1011305 N6-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication.
Pan P et al. Signal Transduct Target Ther 2023; 8 (1):194 SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication.
Myers ML et al. Nat Commun 2023; 14 (1):1763 Commercial influenza vaccines vary in HA-complex structure and in induction of cross-reactive HA antibodies.
Application : IHC-P
Chen J et al. Virol Sin 2023; 38 (1):128-141 Nonmuscle myosin IIA promotes the internalization of influenza A virus and regulates viral polymerase activity through interacting with nucleoprotein in human pulmonary cells.
Application : WB, ICC/IF
G?nl F et al. Nat Commun 2023; 14 (1):787 The ubiquitination landscape of the influenza A virus polymerase.
Application : WB
Panagiotidis GD et al. Arch Virol 2023; 168 (2):63 Influenza A virus strain PR/8/34, but neither HAM/2009 nor WSN/33, is transiently inhibited by the PB2-targeting drug paliperidone.
Application : WB, IP
Chen Y et al. Influenza Other Respir Viruses 2023; 17 (3):e13112 Antiviral effect and mechanism of Phillyrin and its reformulated FS21 against influenza.
Application : WB
Hui X et al. Antiviral Res 2023; 209:105465 In vitro and in vivo effects of 3-indoleacetonitrile-A potential new broad-spectrum therapeutic agent for SARS-CoV-2 infection.
Hao Q et al. Front Immunol 2022; 13:1011922 Inducible general knockout of Runx3 profoundly reduces pulmonary cytotoxic CD8+ T cells with minimal effect on outcomes in mice following influenza infection.
Application : IHC-P
Xiao YN et al. Viruses 2022; 14 (12) Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta.
Jiang J et al. iScience 2022; 25 (7):104607 LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination.
Zheng H et al. J Virol 2022; 96 (12):e0049422 G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2.
Application : WB
Diefenbacher M et al. J Virol 2022; 96 (10):e0020522 Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression.
Application : WB
Huang Y et al. Viruses 2022; 14 (12) Nisoldipine Inhibits Influenza A Virus Infection by Interfering with Virus Internalization Process.
Li Q et al. Adv Sci (Weinh) 2022; 9 (34):e2203088 SRSF5-Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host-Directed Target Against Influenza Virus.
French H et al. Sci Adv 2022; 8 (36):eabp8655 Transient RNA structures cause aberrant influenza virus replication and innate immune activation.
Jiahui Zou et al. Int J Mol Sci 2022; 23 (8) Transportin-3 Facilitates Uncoating of Influenza A Virus.
Jianyuan Zhao et al. Nat Commun 2022; 13 (1):2079 An anti-influenza A virus microbial metabolite acts by degrading viral endonuclease PA.
Application : WB
Wang J et al. Cell Death Discov 2022; 8 (1):97 Osteopontin aggravates acute lung injury in influenza virus infection by promoting macrophages necroptosis.
Application : WB
Kun Huang et al. Front Vet Sci 2021; 8:808234 139D in NS1 Contributes to the Virulence of H5N6 Influenza Virus in Mice.
Application : IHC-P
Amol Patil et al. J Virol 2021; 95 (6) Phosphorylation of Influenza A Virus NS1 at Serine 205 Mediates Its Viral Polymerase-Enhancing Function.
Application : WB
Yaxin Zhao et al. Int J Mol Sci 2021; 22 (11) CMAS and ST3GAL4 Play an Important Role in the Adsorption of Influenza Virus by Affecting the Synthesis of Sialic Acid Receptors.
Application : WB
Masahiro Nakano et al. Commun Biol 2021; 4 (1):858 Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis.
Application : ICC/IF
Xin Mao et al. Evid Based Complement Alternat Med 2021; 2021:5547424 Essential Oil-Rich Chinese Formula Luofushan-Baicao Oil Inhibits the Infection of Influenza A Virus through the Regulation of NF-κB P65 and IRF3 Activation.
Application : WB, ICC/IF
Vanessa Gerlt et al. Int J Mol Sci 2021; 22 (20) Cellular Protein Phosphatase 2A Regulates Cell Survival Mechanisms in Influenza A Virus Infection.
Application : WB, ICC/IF
Wu XX et al. Virol J 2021; 18 (1):237 The viral distribution and pathological characteristics of BALB/c mice infected with highly pathogenic Influenza H7N9 virus.
Application : IHC-P
Froggatt HM et al. PLoS Pathog 2021; 17 (9):e1009951 Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity.
Application : WB
Huang K et al. Microbiol Spectr 2021; 9 (2):e0073421 PGRMC1 Exerts Its Function of Anti-Influenza Virus in the Central Nervous System.
Application : IHC-P
Ulferts R et al. Cell Rep 2021; 37 (4):109899 Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation.
Kinoshita T et al. Sci Rep 2021; 11 (1):21259 Co-infection of SARS-CoV-2 and influenza virus causes more severe and prolonged pneumonia in hamsters.
Application : IHC-P
Gopal V et al. ACS Appl Mater Interfaces 2021; 13 (26):30317-30325 Zinc-Embedded Polyamide Fabrics Inactivate SARS-CoV-2 and Influenza A Virus.
Application : WB
Hara H et al. Sci Rep 2021; 11 (1):10109 Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells.
Application : WB
Oh SJ et al. Cells 2021; 10 (3) SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response.
Application : WB
Liu Y et al. Vet Microbiol 2021; 254:108997 The inactivated vaccine of reassortant H3N2 canine influenza virus based on internal gene cassette from PR8 is safe and effective.
Gong W et al. J Virol 2021; Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly.
Application : WB, ICC/IF
Wang B et al. Front Microbiol 2021; 12:593202 Differences in Highly Pathogenic H5N6 Avian Influenza Viral Pathogenicity and Inflammatory Response in Chickens and Ducks.
Application : IHC-P
Chida J et al. PLoS Pathog 2020; 16 (8):e1008823 Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice.
Application : WB
Zhu Y et al. Sci Adv 2020; 6 (25):eaaz5764 Human TRA2A determines influenza A virus host adaptation by regulating viral mRNA splicing.
Lambertz RLO et al. Virol J 2020; 17 (1):56 H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice.
Gopal V et al. bioRxiv 2020; (Epub) Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus.
Application : WB
Gao Q et al. J Virol 2020; 95 (2) Eukaryotic Translation Elongation Factor 1 Delta Inhibits the Nuclear Import of the Nucleoprotein and PA-PB1 Heterodimer of Influenza A Virus.
Application : WB
Luo Z et al. Signal Transduct Target Ther 2020; 5 (1):202 Novel insights into stress-induced susceptibility to influenza: corticosterone impacts interferon-β responses by Mfn2-mediated ubiquitin degradation of MAVS.
Application : WB
Percopo CM et al. Viruses 2020; 12 (9) Alternaria alternata Accelerates Loss of Alveolar Macrophages and Promotes Lethal Influenza A Infection.
Application : IHC-P
Zhang Q et al. Microbes Infect 2020; (Epub) SNW1 interacts with IKKγ to positively regulate antiviral innate immune responses against influenza A virus infection.
Application : WB
Chida J et al. PLoS Pathog 2020; 16 (8):e1008823 Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice.
Application : WB
Zhang X et al. Front Microbiol 2020; 11:538355 Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins.
Application : WB
Bao J et al. Front Microbiol 2020; 11:1293 Galectin-1 Ameliorates Influenza A H1N1pdm09 Virus-Induced Acute Lung Injury.
Application : IHC-P
Makau JN et al. Viruses 2020; 12 (3) A Quinolinone Compound Inhibiting the Oligomerization of Nucleoprotein of Influenza A Virus Prevents the Selection of Escape Mutants.
Application : ICC/IF
Wu XX et al. Emerg Microbes Infect 2020; 9 (1):962-975 Novel pathogenic characteristics of highly pathogenic avian influenza virus H7N9: viraemia and extrapulmonary infection.
Application : IHC-P
Hu A et al. Front Microbiol 2020; 11:178 Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase.
Application : WB
Zhang T et al. Cell 2020; 180 (6):1115-1129 Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.
Application : WB
Chen WC et al. J Med Chem 2020; 63 (3):1313-1327 Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections.
Cai M et al. Viruses 2020; 12 (1) The R251K Substitution in Viral Protein PB2 Increases Viral Replication and Pathogenicity of Eurasian Avian-like H1N1 Swine Influenza Viruses.
Application : WB
Luo Z et al. Front Pharmacol 2019; 10:78 Epigoitrin, an Alkaloid From Isatis indigotica, Reduces H1N1 Infection in Stress-Induced Susceptible Model in vivo and in vitro.
Chao TL et al. Front Microbiol 2019; 10:2942 Characterization of Influenza A Virus Infection in Mouse Pulmonary Stem/Progenitor Cells.
Application : WB
Hao X et al. Transbound Emerg Dis 2019; (Epub) The PB2 and M genes are critical for the superiority of genotype S H9N2 virus to genotype H in optimizing viral fitness of H5Nx and H7N9 avian influenza viruses in mice.
Application : WB
Ciminski K et al. Nat Microbiol 2019; Bat influenza viruses transmit among bats but are poorly adapted to non-bat species.
Application : WB
Park YH et al. J Infect Dis 2019; Host-specific restriction of avian influenza virus caused by differential dynamics of ANP32 family members.
Application : ICC/IF
Choi JG et al. Sci Rep 2019; 9 (1):12132 Antiviral activity of ethanol extract of Geranii Herba and its components against influenza viruses via neuraminidase inhibition.
Application : WB
Hao X et al. Virology 2019; 535:218-226 The PB2 and M genes of genotype S H9N2 virus contribute to the enhanced fitness of H5Nx and H7N9 avian influenza viruses in chickens.
Application : WB
Zheng W et al. Cell Rep 2019; 27 (6):1875-1885.e5 Naproxen Exhibits Broad Anti-influenza Virus Activity in Mice by Impeding Viral Nucleoprotein Nuclear Export.
Application : ICC/IF
Zhao L et al. Mol Ther Nucleic Acids 2019; 14:509-519 The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2.
Application : WB
Zhang J et al. Eur J Pharm Sci 2019; 133:86-94 Identification of NMS-873, an allosteric and specific p97 inhibitor, as a broad antiviral against both influenza A and B viruses.
Application : WB
Ciminski K et al. Emerg Microbes Infect 2019; 8 (1):556-563 Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11.
Application : WB
Mohl G et al. Antiviral Res 2019; 164:81-90 Novel influenza inhibitors designed to target PB1 interactions with host importin RanBP5.
Chida J et al. PLoS Pathog 2018; 14 (5):e1007049 Prion protein protects mice from lethal infection with influenza A viruses.
Application : ICC/IF, IHC-P
Guo K et al. Oncotarget 2018; 9 (9):8350-8367 Proteomic analysis of chicken embryo fibroblast cells infected with recombinant H5N1 avian influenza viruses with and without NS1 eIF4GI binding domain.
Wang B et al. Front Immunol 2018; 9:1193 Influenza A Virus Facilitates Its Infectivity by Activating p53 to Inhibit the Expression of Interferon-Induced Transmembrane Proteins.
Lambertz RLO et al. J Gen Virol 2018; 99 (9):1187-1198 Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice.
Wohlgemuth N et al. J Virol 2018; 92 (22) Influenza A Virus M2 Protein Apical Targeting Is Required for Efficient Virus Replication.
Te Velthuis AJW et al. Nat Microbiol 2018; 3 (11):1234-1242 Mini viral RNAs act as innate immune agonists during influenza virus infection.
Lin HT et al. Sci Rep 2018; 8 (1):17242 Grail attenuates influenza A virus infection and pathogenesis by inhibiting viral nucleoprotein.
Application : WB
Yang C et al. J Virol 2018; (Epub) The nucleolar protein LYAR facilitates ribonucleoprotein assembly of influenza A virus.
Application : WB, ICC/IF
Mizuta S et al. ChemMedChem 2018; (Epub) Synthesis of Trifluoromethyl-α,β-unsaturated Lactones and Pyrazolinones and Discovery of Influenza Virus Polymerase Inhibitors.
Application : WB
Wang J et al. Viruses 2018; 10 (6) Host Long Noncoding RNA lncRNA-PAAN Regulates the Replication of Influenza A Virus.
Application : WB
Wessels U et al. J Virol 2018; (Epub) A dual motif in the hemagglutinin of H5N1 Goose/Guangdong-like HPAIV is conserved from their early evolution and increases both membrane fusion pH and virulence.
Application : WB
Chen L et al. Virus Res 2018; 252:22-28 N-myc downstream-regulated gene 1 facilitates influenza A virus replication by suppressing canonical NF-κB signaling.
Application : WB
Chida J et al. PLoS Pathog 2018; 14 (5):e1007049 Prion protein protects mice from lethal infection with influenza A viruses.
Application : WB
Aartjan te Velthuis et al. bioRxiv 2018; (Epub) Mini viral RNAs act as innate immune agonists during influenza virus infection.
Application : WB
Chen L et al. Front Immunol 2017; 8:1757 Histone Deacetylase 1 Plays an Acetylation-Independent Role in Influenza A Virus Replication.
Giese S et al. Nat Commun 2017; 8 (1):1259 Role of influenza A virus NP acetylation on viral growth and replication.
Guo K et al. Oncotarget 2017; (Epub) Proteomic analysis of chicken embryo fibroblast cells infected with recombinant H5N1 avian influenza viruses with and without NS1 eIF4GI binding domain.
Application : WB
Rowell J et al. Vaccine 2017; (Epub) Conventional influenza vaccines influence the performance of a universal influenza vaccine in mice.
Application : WB
Giese S et al. Nat. Commun. 2017; (Epub) Role of influenza A virus NP acetylation on viral growth and replication.
Application : WB
Liu H et al. J Virol 2017; (Epub) Mutations in the Influenza A virus * protein enhance virus budding to complement lethal mutations in the M2 cytoplasmic tail.
Application : WB
Sutton TC et al. J Virol 2017; (Epub) In vitro neutralization is not predictive of prophylactic efficacy of broadly neutralizing monoclonal antibodies CR6261 and CR9114 against lethal H2 influenza virus challenge in mice.
Application : IHC-P
Hu Y et al. Int J Mol Sci 2017; 18 (9) Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral.
Application : WB
Watanabe K et al. Sci Rep 2017; 7 (1):9500 Structure-based drug discovery for combating influenza virus by targeting the PA-PB1 interaction.
Application : WB
Hu Y et al. Antiviral Res 2017; 145:103-113 Discovery of dapivirine, a nonnucleoside HIV-1 reverse transcriptase inhibitor, as a broad-spectrum antiviral against both influenza A and B viruses.
Application : WB
Qian W et al. Front. Immunol. 2017; (Epub) The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-β Production by Targeting TNF Receptor-Associated Factor 3.
Application : WB
Czako R et al. MBio 2017; 8 (3) In Vivo Imaging of Influenza Virus Infection in Immunized Mice.
Application : IHC-P
Zhang S et al. Int J Mol Sci 2017; 18 (4) Sus scrofa miR-204 and miR-4331 Negatively Regulate Swine H1N1/2009 Influenza A Virus Replication by Targeting Viral HA and NS, Respectively.
Application : WB
Makau JN et al. PLoS One 2017; 12 (3):e0173582 Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches.
Application : WB
Sun H et al. Sci Rep 2015; 5:10130 The infection of turkeys and chickens by reassortants derived from pandemic H1N1 2009 and avian H9N2 influenza viruses.
Application : WB
Li YT et al. PLoS One 2015; 10 (8):e0133910 Phenotypic and Genetic Characterization of Avian Influenza H5N2 Viruses with Intra- and Inter-Duck Variations in Taiwan.
Application : WB
Zhang Z et al. Sci Rep 2015; 5:17809 Infectious Progeny of 2009 A (H1N1) Influenza Virus Replicated in and Released from Human Neutrophils.
Application : WB
Tawaratsumida K et al. J Virol 2014; 88 (16):9038-48 Quantitative proteomic analysis of the influenza A virus nonstructural proteins NS1 and NS2 during natural cell infection identifies PACT as an NS1 target protein and antiviral host factor.
Application : WB
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