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Signaling Pathways

Cell signaling refers to the various sequences of molecular events that mark a cell’s response to its environment, whether that entails interaction with another cell or other external cues. In the most fundamental sense, this allows an extracellular stimulus to exert an effect across the cell membrane through its transduction into a biochemical currency that in most cases will affect gene expression and the cell’s physiological functioning or identity. A common flow for a signaling pathway involves the binding of a ligand to a receptor, protein modification by enzymes like kinases, assembly of signaling complexes and activation of secondary messengers, and ultimately alterations in the actions of transcription factors or other effectors of the transcriptome or proteome. In summary, cell signaling defines the very notion of a cell being alive.

GeneTex offers an extensive catalog of antibody reagents to study key receptors and their associated signaling pathways. Please click on the pathway links on the left for additional relevant product information.

Pathways
Wnt Pathway

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Pathways
Epithelial–mesenchymal transition (EMT) Pathway

Epithelial–mesenchymal transition (EMT) Pathway

EMT is a process whereby tightly-interacting and immotile epithelial cells acquire the phenotype of loosely-adherent and motile mesenchymal cells.
Literature
Flyer - Post-Translational Modifications

Flyer - Post-Translational Modifications

Download the latest version of GeneTex's post-translational modifications flyer.
Literature
Flyer - EGFR Signaling

Flyer - EGFR Signaling

Download the latest version of GeneTex's EGFR signaling flyer.
Literature
Flyer - mTOR Signaling Pathway

Flyer - mTOR Signaling Pathway

Download the latest version of GeneTex's mTOR signaling pathway flyer.
Literature
Pamphlet - Hot Products

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Flyer - Post-Translational Modifications

Flyer - Post-Translational Modifications

Download the latest version of GeneTex's post-translational modifications flyer.
Literature
Flyer - EGFR Signaling

Flyer - EGFR Signaling

Download the latest version of GeneTex's EGFR signaling flyer.
Literature
Flyer - mTOR Signaling Pathway

Flyer - mTOR Signaling Pathway

Download the latest version of GeneTex's mTOR signaling pathway flyer.
Literature
Pamphlet - Hot Products

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.