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Claudin 3 antibody [HMV309] HistoMAX™

Recombinant antibody HistoMAX
Anti-Claudin 3 antibody [HMV309] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639933
Anti-Claudin 3 antibody [HMV309] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639933
Anti-Claudin 3 antibody [HMV309] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639933

Cat. No. GTX639933

Host

Rabbit

Clonality

Monoclonal

Clone Name

HMV309

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($649),
100 μl ($329)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Target Retrieval Solution buffer.

Not tested in other applications.

Product Note

This antibody was raised against human Claudin 3 Intracellular domain.

Predict Reactivity

Bovine, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.77 mg/ml

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human Claudin 3. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

claudin 3,C7orf1,CPE-R2,CPETR2,HRVP1,RVP1

Cellular Localization

Cell membrane

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Claudin 3 antibody [HMV309] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639933

GTX639933 IHC-P Image

IHC-P analysis of human fallopian tube mucosa tissue using GTX639933 Claudin 3 antibody [HMV309] HistoMAX™.
Strong membranous claudin 3 staining of epithelial cells.

Anti-Claudin 3 antibody [HMV309] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639933

GTX639933 IHC-P Image

IHC-P analysis of human submandibular gland from mouth tissue using GTX639933 Claudin 3 antibody [HMV309] HistoMAX™.
Strong membranous claudin 3 staining of glandular cells. Claudin 3 staining is only very faint in excretory duct cells.

Anti-Claudin 3 antibody [HMV309] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639933

GTX639933 IHC-P Image

IHC-P analysis of human muscle-invasive bladder cancer (MIBC) tissue using GTX639933 Claudin 3 antibody [HMV309] HistoMAX™.
Muscle-invasive urothelial carcinoma with strong claudin 3 positivity of tumor cells.

REFERENCE

There are currently no references for Claudin 3 antibody [HMV309] HistoMAX™ (GTX639933). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Claudin 3 antibody [HMV309] HistoMAX™ (GTX639933). Be the first to share your experience with this product.
Package List Price ($)
$ 649
$ 329