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Tumor Suppressor Proteins

Tumor Suppressor Proteins

Tumor suppressor gene products act as barriers to block cells from proceeding down the path to cancer. In contrast to the protein products of proto-oncogenes, some tumor suppressor proteins act to restrain abnormal cell proliferation. Others promote cell death pathways or function in DNA repair. While mutated proto-oncogenes behave in a dominant fashion, tumor suppressor genes are generally recessive, thus requiring that both be inactivated or otherwise compromised in order for cancers to occur. Well-described examples of tumor suppressor genes include RB1, TP53, APC and CDKN2A.
 
 

Highlighted Products

HIF1 alpha antibody  (GTX628480)
 

HIF1 beta antibody (GTX128795)
 

HIF2 alpha antibody  (GTX632015)
 
 
 

CAIX antibody  (GTX70020)
 

Heme Oxygenase 1 antibody (GTX101147)
 

PHD2 antibody (GTX132293)
 
 
 

PKM antibody (GTX107977)
 

MMP2 antibody (GTX104577)
 

VEGF antibody (GTX102643)
 
 
 

VE-cadherin antibody  (GTX633705)
 
     
 
 
 
 

 

Pathways
Wnt Pathway

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Literature
Poster - Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature
Pamphlet - Hot Products

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Pamphlet - Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
Poster - Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature
Pamphlet - Hot Products

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Pamphlet - Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research