MyD88 antibody, Internal

Cat. No. GTX89605

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA, Sandwich ELISA
Reactivity	Human
Package	100 μg ($399)

See all MyD88 products

Datasheet
Document

View product citations for antibody GTX89605 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	0.1-0.3μg/ml
IHC-P	4-6μg/ml
ELISA	Assay dependent
Sandwich ELISA	Assay dependent
Note : IHC-P Human Tonsil shows staining of clusters of cells some of which are likely plasma cells.

Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89605-PEP).

Product Note

This antibody is expected to recognize reported isoforms 1, 2 and 3 (NP_001166038.1; NP_002459.2; NP_001166039.1).

Predict Reactivity

Mouse, Rat, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-IKYKAMKKEFP, from the internal region of the protein sequence according to NP_001166038.1; NP_002459.2; NP_001166039.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MYD88 innate immune signal transduction adaptor , MYD88D

Cellular Localization

Cytoplasm , Nucleus

Background

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Database

Gene ID: 4615 MYD88
UniProt: Q99836 MYD88

Research Area

DATA IMAGES

GTX89605 WB Image

WB analysis of human thymus lysate using GTX89605 MyD88 antibody, Internal.
Dilution : 0.2μg/ml
Loading : 35μg protein in RIPA buffer

GTX89605 ELISA Image

ELISA analysis of MyD88 protein using GTX89605 MyD88 antibody, Internal.
Capture : GTX112986 (5μg/ml)
Detection : GTX89605 (5μg/ml)

GTX89605 IHC-P Image

IHC-P analysis of human tonsil using GTX89605 MyD88 antibody, Internal.
Antigen retrieval : Tris/EDTA buffer pH 9
Dilution : 4μg/ml

REFERENCE

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SDS
Sodium Azide.pdf

Package

List Price ($)

100 μg

$ 399

Qty