Adrenal gland

Aorta, media

Appendix, mucosa – Complete absence of PAPP A immunostaining in epithelial and stromal cells of the appendix mucosa.

Appendix, muscular wall

Bone marrow

Breast

Bronchus, mucosa

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)

Cerebellum (white matter)

Cerebrum (grey matter)

Cerebrum (white matter)

Colon descendens, mucosa

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, mucosa

Epididymis

Esophagus, squamous epithelium

Fallopian tube, mucosa

Fat

Gallbladder, epithelium

Heart muscle

Ileum, mucosa

Kidney, cortex

Kidney, medulla

Liver

Lung

Lymph node

Ovary, stroma

Pancreas

Parathyroid gland

Parotid gland

Pituitary gland (anterior lobe)

Pituitary gland (posterior lobe)

Placenta (amnion and chorion) – Chorion cells show moderate to strong PAPP A immunostaining. Staining is also seen in the stroma, probably due to the „secreted“ nature of the protein.

Placenta (first trimester) – Trophoblast cells of a first trimester placenta exhibiting a moderate to strong PAPP A immunostaining.

Placenta (first trimester) – Strong PAPP A immunostaining of trophoblast cells of a first trimester placenta.

Placenta, mature – Syncytiotrophoblast cells show strong PAPP A immunostaining in a mature placenta.

Prostate

Rectum, mucosa

Seminal vesicle

Sinus paranasales, mucosa

Skeletal muscle

Skin

Spleen

Stomach, antrum

Stomach, corpus

Testis

Thymus

Thyroid gland

Tonsil, surface epithelium

Tonsil

Urinary bladder, muscular wall

Urinary bladder, urothelium

Uterus, ectocervix

Uterus, endocervix

Uterus, endometrium (pregnancy) – Few scattered chorion cells show moderate PAPP A immunostaining.

Uterus, endometrium (pregnancy)

Uterus, endometrium (proliferation)

Uterus, endometrium (secretion)

Uterus, myometrium