GeneTex
United States (US)
Monoclonal Antibodies

Monoclonal Antibodies

Monoclonal antibodies are produced by immortal hybridoma cells created from the fusion of antibody-producing splenic B-cells and myeloma cells, or by recombinant protein expression in mammalian cells. These antibodies have monovalent affinity and bind to a single epitope on the antigen. Purification is commonly accomplished through Protein A/G/L affinity chromatography.

GeneTex offers a broad selection of monoclonal antibodies directed against the majority of key targets/proteins in the spectrum of biomedical research.

Monoclonal Antibodies
Articles

Five Pillars of Antibody Validation

GeneTex employs various analytic validation strategies to ensure both consistent quality and specificity.
Articles
beta Amyloid

beta Amyloid

GeneTex’s “beta-Amyloid (1-42) antibody – Conformation-Specific” can specifically detect amyloid plaques in the Alzheimer's Disease brain by IHC-P analysis. The superior specificity and sensitivity of this antibody were confirmed by dot blot, ELISA and side-by-side IHC-P comparison with competitor's.
Articles

Approach to Antibody Lot-to-Lot Variability

Lot-to-lot variability is a persistent quality control (QC) issue that contributes to inconsistent results in assays using antibodies.
Promotion

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Articles

Overexpression Antibodies

The validity of a target protein’s endogenous signal can be further substantiated through overexpression of that protein using a recombinant construct.
Articles

Orthogonal_Antibodies

Detecting predicted changes in the antibody-generated signal due to alteration of experimental biological conditions is a reliable approach to gauge antibody performance.
Articles

IP/MS-antibodies

Using mass spectrometry (MS) to identify the protein(s) bound by an antibody is a powerful method for the validation of antibody specificity and performance.
Promotion

25μl package available!

Our most popular antibodies now come in 25μl packaging.
Articles

Knockout/Knockdown Validation

GeneTex is conducting knockout/knockdown-based validation as a fundamental component of its antibody quality assurance process.
Pathways

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Protocols

Protocol - Western Blot

Download GeneTex's Western Blot Protocol.
Protocols

Protocol - ICC/IF

Download GeneTex's ICC/IF Protocol.
Protocols

Protocol - IHC (paraffin)

Download GeneTex's IHC (paraffin) Protocol.
Protocols

Protocol - IHC (frozen)

Download GeneTex's IHC (frozen) Protocol.
Protocols

Protocol - IHC (whole-mount)

Download GeneTex's IHC (whole-mount) Protocol.
Protocols

Protocol - Immunoprecipitation

Download GeneTex's Immunoprecipitation Protocol.
Protocols

Protocol - ELISA (sandwich)

Download GeneTex's ELISA (sandwich) Protocol.
Protocols

Protocol - ELISA (indirect)

Download GeneTex's ELISA (indirect) Protocol.
Protocols

Protocol - Flow Cytometry

Download GeneTex's Flow Cytometry Protocol.
Protocols

Protocol - Dot Blot

Download GeneTex's Dot Blot Protocol.
Protocols

Protocol - Blocking Peptide Competition

Download GeneTex's Blocking Peptide Competition Protocol.
Literature

Flyer - Five Pillars Validation

Download the latest version of GeneTex's epitope five pillars validation flyer.
Literature

Flyer - Loading Controls

Download the latest version of GeneTex's loading controls flyer.
Literature

Pamphlet - Western Blot Troubleshooting

Download the latest version of GeneTex's pamphlet for western blot troubleshooting.
Literature

Flyer - Upgrade Your Western Blot Results

Download the latest version of GeneTex's flyer for upgrade your western blot results.
Literature

Flyer - IHC Troubleshooting Guide

Download the latest version of GeneTex's IHC troubleshooting guide flyer.
Literature

Flyer - Epitope Tags and Reporters

Download the latest version of GeneTex's epitope tags and reporters flyer.
Literature

Flyer - Five Pillars Validation

Download the latest version of GeneTex's epitope five pillars validation flyer.
Literature

Flyer - Loading Controls

Download the latest version of GeneTex's loading controls flyer.
Literature

Pamphlet - Western Blot Troubleshooting

Download the latest version of GeneTex's pamphlet for western blot troubleshooting.
Literature

Flyer - Upgrade Your Western Blot Results

Download the latest version of GeneTex's flyer for upgrade your western blot results.
Literature

Flyer - IHC Troubleshooting Guide

Download the latest version of GeneTex's IHC troubleshooting guide flyer.
Literature

Flyer - Epitope Tags and Reporters

Download the latest version of GeneTex's epitope tags and reporters flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Articles

Five Pillars of Antibody Validation

GeneTex employs various analytic validation strategies to ensure both consistent quality and specificity.
Articles
beta Amyloid

beta Amyloid

GeneTex’s “beta-Amyloid (1-42) antibody – Conformation-Specific” can specifically detect amyloid plaques in the Alzheimer's Disease brain by IHC-P analysis. The superior specificity and sensitivity of this antibody were confirmed by dot blot, ELISA and side-by-side IHC-P comparison with competitor's.
Articles

Approach to Antibody Lot-to-Lot Variability

Lot-to-lot variability is a persistent quality control (QC) issue that contributes to inconsistent results in assays using antibodies.
Articles

Overexpression Antibodies

The validity of a target protein’s endogenous signal can be further substantiated through overexpression of that protein using a recombinant construct.
Articles

Orthogonal_Antibodies

Detecting predicted changes in the antibody-generated signal due to alteration of experimental biological conditions is a reliable approach to gauge antibody performance.
Articles

IP/MS-antibodies

Using mass spectrometry (MS) to identify the protein(s) bound by an antibody is a powerful method for the validation of antibody specificity and performance.
Articles

Knockout/Knockdown Validation

GeneTex is conducting knockout/knockdown-based validation as a fundamental component of its antibody quality assurance process.
Articles

ResponsibleScientists.org

An Open Letter Regarding Climate Change From Concerned Members of the U.S. National Academy of Sciences
Protocols

Protocol - Western Blot

Download GeneTex's Western Blot Protocol.
Protocols

Protocol - ICC/IF

Download GeneTex's ICC/IF Protocol.
Protocols

Protocol - IHC (paraffin)

Download GeneTex's IHC (paraffin) Protocol.
Protocols

Protocol - IHC (frozen)

Download GeneTex's IHC (frozen) Protocol.
Protocols

Protocol - IHC (whole-mount)

Download GeneTex's IHC (whole-mount) Protocol.
Protocols

Protocol - Immunoprecipitation

Download GeneTex's Immunoprecipitation Protocol.
Protocols

Protocol - ELISA (sandwich)

Download GeneTex's ELISA (sandwich) Protocol.
Protocols

Protocol - ELISA (indirect)

Download GeneTex's ELISA (indirect) Protocol.
Protocols

Protocol - Flow Cytometry

Download GeneTex's Flow Cytometry Protocol.
Protocols

Protocol - Dot Blot

Download GeneTex's Dot Blot Protocol.
Protocols

Protocol - Blocking Peptide Competition

Download GeneTex's Blocking Peptide Competition Protocol.