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AKR1C1 antibody [AT6D10]

Anti-AKR1C1 antibody [AT6D10] used in Western Blot (WB). GTX53684

Cat. No. GTX53684

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AT6D10

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all AKR1C1 products

APPLICATION

Application Note

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000. Recommended starting dilution is 1:1000

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human AKR1C1 (1-323aa) purified from E. coli

Purification

By protein-G affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887820

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aldo-keto reductase family 1 member C1 , 2-ALPHA-HSD , 20-ALPHA-HSD , C9 , DD1 , DD1/DD2 , DDH , DDH1 , H-37 , HAKRC , HBAB , MBAB

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-AKR1C1 antibody [AT6D10] used in Western Blot (WB). GTX53684

GTX53684 WB Image

WB analysis of HepG2 lysate (33ug per lane) using AKR1C1 antibody at the indicated dilutions.

REFERENCE

Application Reference

Manandhar M et al. DNA Repair (Amst) 2017; 57 : 76-90 Transcriptional consequences of XPA disruption in human cell lines.
Application : WB
Reactivity : Human
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399