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Alpha fetoprotein / AFP antibody [C3]

Anti-Alpha fetoprotein / AFP antibody [C3] used in IHC (Paraffin sections) (IHC-P). GTX34405

Cat. No. GTX34405

Host

Mouse

Clonality

Monoclonal

Clone Name

C3

Isotype

IgG2a

Application

IHC-P

Reactivity

Human, Dog, Pig, Monkey
Package
100 μg ($529)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

69 kDa. ( Note )

Product Note

This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin.
We do not recommend use of this product for Mouse,Rat,Bovine samples.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Alpha feto protein (AFP) Purified from serum of a hepatoma patient

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AFP , AFPD , FETA , HPAFP , alpha fetoprotein

Cellular Localization

Secreted

Background

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]

Database

Research Area

DATA IMAGES

Anti-Alpha fetoprotein / AFP antibody [C3] used in IHC (Paraffin sections) (IHC-P). GTX34405

GTX34405 IHC-P Image

IHC-P analysis of human fetal liver tissue using GTX34405 Alpha fetoprotein / AFP antibody [C3].

REFERENCE

There are currently no references for Alpha fetoprotein / AFP antibody [C3] (GTX34405). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Alpha fetoprotein / AFP antibody [C3] (GTX34405). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529