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Brachyury antibody [HMV321] HistoMAX™

Recombinant antibody HistoMAX
Anti-Brachyury antibody [HMV321] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639945
Anti-Brachyury antibody [HMV321] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639945
Anti-Brachyury antibody [HMV321] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639945

Cat. No. GTX639945

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HMV321

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649),
100 μl ($329)
See all Brachyury products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent

Antigen Species

Human

Immunogen

Recombinant fragment of human Brachyury.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

T-box transcription factor T,SAVA,T,TFT

Cellular Localization

Nucleus

Background

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018]

Database

Research Area

DATA IMAGES

Anti-Brachyury antibody [HMV321] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639945

GTX639945 IHC-P Image

IHC-P analysis of human bone chordoma tissue using GTX639945 Brachyury antibody [HMV321] HistoMAX™.
Chordoma with intense brachyury staining of all tumor cells.

Anti-Brachyury antibody [HMV321] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639945

GTX639945 IHC-P Image

IHC-P analysis of human bone chondrosarcoma tissue using GTX639945 Brachyury antibody [HMV321] HistoMAX™.
Brachyury negative chondrosarcoma.

Anti-Brachyury antibody [HMV321] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639945

GTX639945 IHC-P Image

IHC-P analysis of human bone chordoma tissue using GTX639945 Brachyury antibody [HMV321] HistoMAX™.
Chordoma showing strong brachyury staining of tumor cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 649
$ 329
Available soon.