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C4C antibody [99-72-18]

Anti-C4C antibody [99-72-18] used in Immunohistochemistry (IHC). GTX49368
Anti-C4C antibody [99-72-18] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49368
Anti-C4C antibody [99-72-18] used in Immunohistochemistry (IHC). GTX49368
Anti-C4C antibody [99-72-18] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49368
Anti-C4C antibody [99-72-18] used in Immunohistochemistry (IHC). GTX49368
Anti-C4C antibody [99-72-18] used in ELISA (ELISA). GTX49368

Cat. No. GTX49368

Host

Mouse

Clonality

Monoclonal

Clone Name

99-72-18

Isotype

IgG2b

Application

WB, ICC/IF, IP, ELISA, IHC

Reactivity

Human
Package
100 μl ($569)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IP Assay dependent
ELISA Assay dependent
IHC Assay dependent
Not tested in other applications.

Product Note

This antibody binds human complement factor C4c.

PROPERTIES

Form

Liquid

Buffer

10mM Phosphate, 500mM NaCl

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR).

Purification

Protein-A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble). C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa). C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway.

Research Area

DATA IMAGES

Anti-C4C antibody [99-72-18] used in Immunohistochemistry (IHC). GTX49368

GTX49368 IHC Image

IHC staining of human kidney with GTX49368. Strong staining of veins of nephritis kidney. Dilution: 1:600.

Anti-C4C antibody [99-72-18] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49368

GTX49368 ICC/IF Image

IF staining of human kidney with GTX49368. Strong staining of veins of nephritis kidney. Dilution: 1:200.

Anti-C4C antibody [99-72-18] used in Immunohistochemistry (IHC). GTX49368

GTX49368 IHC Image

IHC staining in human tonsil with GTX49368. Plasma in lumen of veins is stained strongly as well as follicular dendritic cells in germinal center of tonsil. Dilution: 1:600.

Anti-C4C antibody [99-72-18] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49368

GTX49368 ICC/IF Image

IF staining in human tonsil with GTX49368. Plasma in lumen of veins is stained strongly in tonsil tissue. Dilution: 1:200.

Anti-C4C antibody [99-72-18] used in Immunohistochemistry (IHC). GTX49368

GTX49368 IHC Image

IHC staining of human liver with GTX49368. Cytoplasm of hepatocytes labelled moderately and plasma of veins strongly in liver tissue. Dilution: 1:600.

Anti-C4C antibody [99-72-18] used in ELISA (ELISA). GTX49368

GTX49368 ELISA Image

The calibration curve of a sandwich assay for Anti-Factor XII using GTX49368 as the capture antibody and GTX60995-02 as the biotinylated detection antibody.

REFERENCE

There are currently no references for C4C antibody [99-72-18] (GTX49368). Be the first to share your publications with this product.

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 569