C9orf72 antibody [GT1553]
Cat. No. GTX634482
Cat. No. GTX634482
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HostMouse
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ClonalityMonoclonal
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Clone NameGT1553
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IsotypeIgG2a
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ApplicationsWB ICC/IF IHC-P
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ReactivityHuman, Mouse, Rat
Summary
C9orf72 antibody detects the C9orf72 protein, which is 481 amino acids in length and has a predicted molecular weight of 54 kDa. The accumulation of abnormal nucleotide repeats in the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), accounting for approximately 34.2% and 25.9% of cases according to van Blitterswijk et al. (PMID: 23160421).