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CCR2 antibody [HL2838]

Recombinant antibody Overexpression
Anti-CCR2 antibody [HL2838] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640109
Anti-CCR2 antibody [HL2838] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640109

Cat. No. GTX640109

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2838

Isotype

 IgG

Application

 ICC/IF

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all CCR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Product Note

This antibody was raised against human CCR2 Extracellular domain.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Extracellular domain of human CCR2. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-C motif chemokine receptor 2 , CC-CKR-2 , CCR-2 , CCR2A , CCR2B , CD192 , CKR2 , CKR2A , CKR2B , CMKBR2 , MCP-1-R

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-CCR2 antibody [HL2838] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640109

GTX640109 ICC/IF Image

CCR2 antibody [HL2838] detects CCR2 protein by immunofluorescent analysis.
Sample: THP-1 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: CCR2 stained by CCR2 antibody [HL2838] (GTX640109) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-CCR2 antibody [HL2838] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640109

GTX640109 ICC/IF Image

Overexpression

CCR2 antibody [HL2838] detects CCR2 protein by immunofluorescent analysis.
Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min.
Green: CCR2 stained by CCR2 antibody [HL2838] (GTX640109) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Available soon.
Custom Conjugations