Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Rat
Immunogen
Splenic PHA blasts
Purification
Purified IgG
Conjugation
Unconjugated
RRID
AB_379316
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
Integrin Subunit Alpha L , Lfa-1 , Itgal
Background
Reacts with the rat LFA-1 a chain (160-170kD) which is associated with the b chain (CD18; 95-100 kD). LFA-1 is one of the leucocyte integrins (b2 integrin) which plays an important role in leucocyte physiology. Functionally, this monoclonal inhibits homotypic aggregation of PHA blasts. It also blocks binding of rat lymphocytes to purified rat ICAM-1.
Research Area