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CD16 antibody [KD1] (PE)

Anti-CD16 antibody [KD1] (PE) used in Flow cytometry (FACS). GTX04886-08

Cat. No. GTX04886-08

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 KD1

Isotype

 IgG2a

Application

 FACS

Reactivity

 Human, Sheep, Bovine, Dolphin
Package
100 test ($499)
See all CD16 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent

Note :

FACS
Use 100μl of the suggested working dilution to label 1x 10⁶ cells in 100μl.
Not tested in other applications.

Calculated MW

29|26 kDa. ( Note )

Product Note

Clone KD1 recognizes both forms of CD16 and will therefore recognize all cell types expressing CD16.
We do not recommend use of this product for Rat,Dog samples.

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 5% Sucrose

Preservative

0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A polyclonal population of NK cells.

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Fc fragment of IgG receptor IIIa , Fc fragment of IgG receptor IIIb , CD16 , CD16A , FCG3 , FCGR3 , FCGRIII , FCR-10 , FCRIII , FCRIIIA , IGFR3 , IMD20 , CD16 , CD16A , CD16b , FCG3 , FCGR3 , FCGR3A , FCR-10 , FCRIII , FCRIIIb

Cellular Localization

Cell membrane,Secreted

Background

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD16 antibody [KD1] (PE) used in Flow cytometry (FACS). GTX04886-08

GTX04886-08 FACS Image

FACS analysis of human blood using GTX04886-08 CD16 antibody [KD1] (PE). Cells were co-stained with GTX00481-06 CD11b antibody [ICRF44] (FITC). The live single granulocytes in the presence of 10% human serum gated for analysis.
Left : Isotype control
Right : Primary antibody

REFERENCE

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REVIEW

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Package List Price ($)
$ 499