CD161 antibody [HP-3G10] (FITC)

Cat. No. GTX01454-06
Cat. No.  GTX01454-06
Anti-CD161 antibody [HP-3G10] (FITC) used in Flow cytometry (FACS). GTX01454-06
GTX01454-06 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX01454-06 CD161 antibody [HP-3G10] (FITC).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.5 μg (5 μl)

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Anti-CD161 antibody [HP-3G10] (FITC) used in Flow cytometry (FACS). GTX01454-06
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Clone Name
    HP-3G10
  • Isotype
    IgG1
  • Applications
    FACS
  • Reactivity
    Human, Baboon, Chimpanzee, Rhesus Monkey
Summary
The HP-3G10 antibody is specific for human CD161, also known as NKR-P1A, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. CD161 exists as a homodimer which is prominently expressed on natural killer (NK) and NKT cells, where it is proposed to regulate the function of both cell types. CD161 is also found on T cell subsets, including T regulatory cells (Tregs), memory/effector CD4+ T cells, and CD8+ T cells. Th17 cells have been demonstrated to co-express CD161, as surface IL-17A+ cells are contained within the CD161+ fraction of CD4 T cells, so that CD161 (in combination with CCR6) is often used as a marker for enrichment of Th17 cells.The HP-3G10 antibody may be used for flow cytometric analysis of CD161 on NK and NKT cells, as well as on various T cell subsets. The antibody is also reported to be cross-reactive with Baboon, Chimpanzee and Rhesus CD161.
See all CD161 products