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CD30 antibody [JCM182]

Anti-CD30 antibody [JCM182] used in IHC (Paraffin sections) (IHC-P). GTX01872

Cat. No. GTX01872

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 JCM182

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($409)
See all CD30 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
Heat Induced Epitope Retreival (HIER) was performed in Citrate-based buffer, pH 6.0. Polymer detection recommended. Using retrieval solutions other than that recommended may increase background reactivity.
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to the internal domain of the protein of the human CD30 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 8 , CD30 , D1S166E , Ki-1

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 943 TNFRSF8
  • UniProt: P28908 TNFRSF8

Research Area

DATA IMAGES

Anti-CD30 antibody [JCM182] used in IHC (Paraffin sections) (IHC-P). GTX01872

GTX01872 IHC-P Image

IHC-P analysis of human lymph node, nodular sclerosing hodgkin's disease tissue using GTX01872 CD30 antibody [JCM182]. Note membrane and cytoplasmic staining of the neoplastic cells, CD30: clone JCM182

REFERENCE

Application Reference

Bing Deng et al. Aging (Albany NY) 2022; 14 (1) : 389-409 Chordin-like 1 is a novel prognostic biomarker and correlative with immune cell infiltration in lung adenocarcinoma.
Application : IHC-P
Reactivity : Human
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REVIEW

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Package List Price ($)
$ 409