CD45R antibody [RA3-6B2] (PE)

Cat. No. GTX00486-08
Cat. No.  GTX00486-08
Anti-CD45R antibody [RA3-6B2] (PE) used in Flow cytometry (FACS). GTX00486-08
GTX00486-08 FACS Image

FACS analysis of C57Bl/6 splenocytes using GTX00486-08 CD45R antibody [RA3-6B2] (PE).
Solid line : Primary antibody
Dashed line : PE rat IgG2a isotype control
Antibody amount : 0.5 μg

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Anti-CD45R antibody [RA3-6B2] (PE) used in Flow cytometry (FACS). GTX00486-08
  • Host
    Rat
  • Clonality
    Monoclonal
  • Clone Name
    RA3-6B2
  • Isotype
    IgG2a
  • Applications
    FACS
  • Reactivity
    Human, Mouse, Cat
Summary
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB, CD45RO and several others.
See all CD45R products