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CD68 antibody [C68/2908R]

Anti-CD68 antibody [C68/2908R] used in Western Blot (WB). GTX02611
Anti-CD68 antibody [C68/2908R] used in IHC (Paraffin sections) (IHC-P). GTX02611

Cat. No. GTX02611

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 C68/2908R

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all CD68 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human LAMP4 / CD68 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD68 molecule , GP110 , LAMP4 , SCARD1

Background

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD68 antibody [C68/2908R] used in Western Blot (WB). GTX02611

GTX02611 WB Image

WB analysis of human Spleen tissue lysate using GTX02611 CD68 antibody [C68/2908R].

Anti-CD68 antibody [C68/2908R] used in IHC (Paraffin sections) (IHC-P). GTX02611

GTX02611 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02611 CD68 antibody [C68/2908R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529