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CD8 antibody [LT8]

Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773
Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773
Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773
Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773

Cat. No. GTX74773

Reference 19

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 LT8

Isotype

 IgG1

Application

 ICC/IF, IHC-Fr, FACS, IP, Blocking

Reactivity

 Human, Mouse, Monkey, Chimpanzee, Cynomolgus monkey, Marmoset, Red-bellied Tamarin
Package
200 μg ($459)
See all CD8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS 1/50-1/100
IP Assay dependent
Blocking Assay dependent

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Normal human peripheral blood lymphocytes.

Purification

Purified by ion exchange chromatography

Conjugation

Unconjugated

RRID

AB_376459

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

P37 Antibody , LYT3 Antibody , CD8B Antibody , LY3 Antibody , LEU2 Antibody , CD8b molecule Antibody , CD8B1 Antibody

Research Area

DATA IMAGES

Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773

GTX74773 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX74773 CD8 antibody [LT8].

Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773

GTX74773 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX74773 CD8 antibody [LT8].

Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773

GTX74773 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX74773 CD8 antibody [LT8].

Anti-CD8 antibody [LT8] used in IHC (Frozen sections) (IHC-Fr). GTX74773

GTX74773 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX74773 CD8 antibody [LT8].

REFERENCE

Application Reference

Qizhi Ma et al. Precis Clin Med 2021; 4 (3) : 155-167 CXCL13 expression in mouse 4T1 breast cancer microenvironment elicits antitumor immune response by regulating immune cell infiltration.
Application : IHC-Fr
Reactivity : Human
Chebloune Y et al. Vaccine 2020; 38 (21) : 3729-3739 A single lentivector DNA based immunization contains a late heterologous SIVmac251 mucosal challenge infection.
Reactivity : Mouse

Clone Reference

Nelson M et al. J Immunol Res 2014; 2014:913632 Exploring the innate immunological response of an alternative nonhuman primate model of infectious disease; the common marmoset.
Kap YS et al. J Immunol 2014; 192 (9):4242-53 CD20+ B cell depletion alters T cell homing.
Application : FACS
Reactivity : Monkey
Hood SP et al. Virus Res 2014; 179:93-101 Changes in immune cell populations in the periphery and liver of GBV-B-infected and convalescent tamarins (Saguinus labiatus).
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REVIEW

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Application Reference
Qizhi Ma et al. Precis Clin Med 2021; 4 (3):155-167 CXCL13 expression in mouse 4T1 breast cancer microenvironment elicits antitumor immune response by regulating immune cell infiltration.
Application : IHC-Fr
Reactivity : Human
Chebloune Y et al. Vaccine 2020; 38 (21):3729-3739 A single lentivector DNA based immunization contains a late heterologous SIVmac251 mucosal challenge infection.
Reactivity : Mouse
Lask A et al. J Immunol 2011; 187 (4):2006-14 TCR-independent killing of B cell malignancies by anti-third-party CTLs: the critical role of MHC-CD8 engagement.
Application : Blocking
Clone Reference
Nelson M et al. J Immunol Res 2014; 2014:913632 Exploring the innate immunological response of an alternative nonhuman primate model of infectious disease; the common marmoset.
Kap YS et al. J Immunol 2014; 192 (9):4242-53 CD20+ B cell depletion alters T cell homing.
Application : FACS
Reactivity : Monkey
Hood SP et al. Virus Res 2014; 179:93-101 Changes in immune cell populations in the periphery and liver of GBV-B-infected and convalescent tamarins (Saguinus labiatus).
Agrawal SM et al. Brain 2013; 136 (Pt 6):1760-77 Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis.
Application : ICC/IF
Reactivity : Human
Held K et al. J Virol 2011; 85 (19):2841710 Expression of herpes simplex virus 1-encoded microRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates.
Hovden AO et al. BMC Immunol 2011; 12:2 Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.
Application : FACS
Nelson M et al. J Med Microbiol 2010; 59 (Pt 9):1107-13 Characterization of lethal inhalational infection with Francisella tularensis in the common marmoset (Callithrix jacchus).
Application : FACS
Buch C et al. J Cell Sci 2009; 122 (Pt 12):73232 An integral protein of the inner nuclear membrane localizes to the mitotic spindle in mammalian cells.
Kap YS et al. J Histochem Cytochem 2009; 57 (12):1159-67 A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.
Lukashevich IS et al. Vaccine 2008; 26 (41):5246-54 Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates.
Junker A et al. Brain 2007; 130 (Pt 11):2789-99 Multiple sclerosis: T-cell receptor expression in distinct brain regions.
Application : IHC-Fr
Gibbings DJ et al. BMC Immunol 2007; 8:12 CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.
Application : FACS
Daubenberger CA et al. Vet Immunol Immunopathol 2007; 119 (43102):14-20 Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research.
Application : FACS
Reactivity : Monkey
Manninen A et al. J Exp Med 2002; 195 (8):1023-32 HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells.
Zarkesh-Esfahani H et al. J Immunol 2001; 167 (8):983844 High-dose leptin activates human leukocytes via receptor expression on monocytes.
Parnes JR et al. Adv Immunol 1989; 44:265-311 Molecular biology and function of CD4 and CD8.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459