APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:1000 |
| 1:100-1:1000 |
Not tested in other applications.
Calculated MW
Product Note
This antibody was raised against human CXCR3 Extracellular domain.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No Preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human CXCR3. The exact sequence is proprietary.
Purification
Affinity purified by Protein A.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-X-C motif chemokine receptor 3 , CD182 , CD183 , CKR-L2 , CMKAR3 , GPR9 , IP10-R , Mig-R , MigR
Cellular Localization
Cell membrane
Background
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]
Database
Research Area
DATA IMAGES
![Anti-CXCR3 antibody [HL3089] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640535](/templates/default/js/lightbox/images/loading.gif "Anti-CXCR3 antibody [HL3089] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640535")
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GTX640535 ICC/IF Image
CXCR3 antibody [HL3089] detects CXCR3 protein by immunofluorescent analysis.Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min.Green: CXCR3 stained by CXCR3 antibody [HL3089] (GTX640535) diluted at 1:500.Blue: Fluoroshield with DAPI (GTX30920).
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GTX640535 IHC-P Image
CXCR3 antibody [HL3089] detects CXCR3 protein by immunohistochemical analysis.Sample: Paraffin-embedded mouse thymus gland.CXCR3 stained by CXCR3 antibody [HL3089] (GTX640535) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX640535 IHC-P Image
CXCR3 antibody [HL3089] detects CXCR3 protein by immunohistochemical analysis.Sample: Paraffin-embedded human breast carcinoma.CXCR3 stained by CXCR3 antibody [HL3089] (GTX640535) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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REFERENCE
There are currently no references for CXCR3 antibody [HL3089] (GTX640535). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CXCR3 antibody [HL3089] (GTX640535). Be the first to share your experience with this product.
![Anti-CXCR3 antibody [HL3089] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640535](/upload/website/prouct_img/small/GTX640535/GTX640535_T-45453_20240802_ICC_IF_B_24081300_290.webp "Anti-CXCR3 antibody [HL3089] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640535")
![Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535](/upload/website/prouct_img/small/GTX640535/GTX640535_T-45453_20240802_IHC-P_M_24081300_546.webp "Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535")
![Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535](/upload/website/prouct_img/small/GTX640535/GTX640535_T-45453_20240802_IHC-P_24081300_901.webp "Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535")
![Anti-CXCR3 antibody [HL3089] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640535](/upload/website/prouct_img/normal/GTX640535/GTX640535_T-45453_20240802_ICC_IF_B_24081300_290.webp "Anti-CXCR3 antibody [HL3089] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX640535")
![Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535](/upload/website/prouct_img/normal/GTX640535/GTX640535_T-45453_20240802_IHC-P_M_24081300_546.webp "Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535")
![Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535](/upload/website/prouct_img/normal/GTX640535/GTX640535_T-45453_20240802_IHC-P_24081300_901.webp "Anti-CXCR3 antibody [HL3089] used in IHC (Paraffin sections) (IHC-P). GTX640535")