Collagen I antibody [COL-1]
Cat. No. GTX26308
Cat. No. GTX26308
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HostMouse
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ClonalityMonoclonal
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Clone NameCOL-1
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IsotypeIgG1
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ApplicationsWB ICC/IF IHC-P IHC-Fr IP Dot ELISA IHC
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ReactivityHuman, Mouse, Rat, Rabbit, Bovine, Pig, Deer
Summary
Collagen I antibody (Collagen 1 antibody) detects type I collagen, a fibrillar type collagen found in almost all connective tissues. The main isoform of type I collagen is a heterotrimer of two α1 and one α2 chains subject to significant posttranslational modification and crosslinking. Mutations in type I collagen are found in osteogenesis imperfecta and Ehlers-Danlos syndrome, but this collagen is also linked to other connective tissue disease as well as disorders associated with aging.