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DPYD antibody [N1N2], N-term

Anti-DPYD antibody [N1N2], N-term used in Western Blot (WB). GTX113672
Anti-DPYD antibody [N1N2], N-term used in Western Blot (WB). GTX113672
Anti-DPYD antibody [N1N2], N-term used in IHC (Paraffin sections) (IHC-P). GTX113672

Cat. No. GTX113672

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all DPYD products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

111 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Bovine, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.59 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human DPYD. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10618118

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dihydropyrimidine dehydrogenase , DHP , DHPDHASE , DPD

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-DPYD antibody [N1N2], N-term used in Western Blot (WB). GTX113672

GTX113672 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with DPYD antibody [N1N2], N-term (GTX113672) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-DPYD antibody [N1N2], N-term used in Western Blot (WB). GTX113672

GTX113672 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with DPYD antibody [N1N2], N-term (GTX113672) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-DPYD antibody [N1N2], N-term used in IHC (Paraffin sections) (IHC-P). GTX113672

GTX113672 IHC-P Image

DPYD antibody [N1N2], N-term detects DPYD protein at cytoplasm on H358 xenograft by immunohistochemical analysis.
Sample: Paraffin-embedded H358 xenograft.
DPYD antibody [N1N2], N-term (GTX113672) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169