APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100-1:1000 |
1:100-1:1000 |
Not tested in other applications.
Calculated MW
Product Note
This antibody was raised against human Dopamine Receptor D1 Extracellular domain.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No Preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human Dopamine Receptor D1. The exact sequence is proprietary.
Purification
Affinity purified by Protein A.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
dopamine receptor D1 , DADR , DRD1A
Cellular Localization
Cell membrane,Endoplasmic reticulum membrane,Cell projection, dendrite,Cell projection, dendritic spine
Background
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX640270 ICC/IF Image
Dopamine Receptor D1 antibody [HL2927] detects Dopamine Receptor D1 protein by immunofluorescent analysis.Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min.Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [HL2927] (GTX640270) diluted at 1:500.Blue: Fluoroshield with DAPI (GTX30920).
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GTX640270 IHC-P Image
Dopamine Receptor D1 antibody [HL2927] detects Dopamine Receptor D1 protein by immunohistochemical analysis.Sample: Paraffin-embedded human MCF-7 xenograft.Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [HL2927] (GTX640270) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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REFERENCE
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REVIEW
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