Dopamine Receptor D4 antibody [HL2851]

Cat. No. GTX640122

Host	Rabbit
Clonality	Monoclonal
Clone Name	HL2851
Isotype	IgG
Application	WB, ICC/IF, IHC-P
Reactivity	Human
Package	100 μl ($399), 25 μl ($169)

See all Dopamine Receptor D4 products

Datasheet

View product citations for antibody GTX640122 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:1000-1:10000
ICC/IF	Assay dependent
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Product Note

This antibody was raised against human Dopamine Receptor D4 Extracellular domain.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Extracellular domain human of Dopamine Receptor D4. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dopamine receptor D4 , D4DR

Cellular Localization

Cell membrane

Background

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]

Database

Gene ID: 1815 DRD4
UniProt: P21917 DRD4

Research Area

DATA IMAGES

GTX640122 WB Image

Non-transfected (–) and transfected (+) boiled and unboiled 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Dopamine Receptor D4 antibody [HL2851] (GTX640122) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX640122 ICC/IF Image

Dopamine Receptor D4 antibody [HL2851] detects Dopamine Receptor D4 protein by immunofluorescent analysis.
Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min.
Green: Dopamine Receptor D4 stained by Dopamine Receptor D4 antibody [HL2851] (GTX640122) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

GTX640122 IHC-P Image

Dopamine Receptor D4 antibody [HL2851] detects Dopamine Receptor D4 protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded human stomach tumor.
Dopamine Receptor D4 stained by Dopamine Receptor D4 antibody [HL2851] (GTX640122) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW

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Package

List Price ($)

100 μl

$ 399

25 μl

$ 169

Qty Custom Conjugations