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FADD antibody

Anti-FADD antibody used in IHC (Paraffin sections) (IHC-P). GTX54024
Anti-FADD antibody used in Immunoprecipitation (IP). GTX54024
Anti-FADD antibody used in Western Blot (WB). GTX54024

Cat. No. GTX54024

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all FADD products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
IP 1:50 - 1:200
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human FADD (NP_003815.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Fas associated via death domain , GIG3 , MORT1

Background

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-FADD antibody used in IHC (Paraffin sections) (IHC-P). GTX54024

GTX54024 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX54024 FADD antibody.
Dilution : 1:200

Anti-FADD antibody used in Immunoprecipitation (IP). GTX54024

GTX54024 IP Image

IP analysis of HeLa cell lysate using GTX54024 FADD antibody.
Antibody amount : 3μg / 200μg lysate
Dilution : 1:1000

Anti-FADD antibody used in Western Blot (WB). GTX54024

GTX54024 WB Image

WB analysis of various sample lysates using GTX54024 FADD antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399