Fas Ligand antibody [NOK-1] (APC)

Cat. No. GTX01476-07
References 2
Cat. No.  GTX01476-07
Anti-Fas Ligand antibody [NOK-1] (APC) used in Flow cytometry (FCM). GTX01476-07
GTX01476-07 FCM Image

FACS analysis of human CD178 (Fas ligand) transfected cells using GTX01476-07 Fas Ligand antibody [NOK-1] (APC).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

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Anti-Fas Ligand antibody [NOK-1] (APC) used in Flow cytometry (FCM). GTX01476-07
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Clone Name
    NOK-1
  • Isotype
    IgG1
  • Applications
    FCM
  • Reactivity
    Human
Summary
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF-α family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
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