Gli1 antibody [HL247]
Cat. No. GTX635619
Cat. No. GTX635619
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HostRabbit
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ClonalityMonoclonal
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Clone NameHL247
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IsotypeIgG
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ApplicationsWB ICC/IF IHC-P IP
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ReactivityHuman, Mouse, Rat
Summary
Gli1 antibody detects Gli1 protein, a zinc-finger protein with a predicted molecular weight of 119 kDa. Gli1 is a transcription factor that serves as an effector of Sonic hedgehog signaling in mediating cell fate during embryonic development. In addition, Gli1 has been shown to control many basic cell functions including the cell cycle, growth, and cell death. Although Gli1 was originally isolated from a glioma tumor, its upregulation is found in many other tumor types.