Human CTLA4 protein, mutant human IgG1 Fc tag (active)
Cat. No. GTX65744-pro
Cat. No. GTX65744-pro
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ApplicationsFunctional Assay
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SpeciesHuman
Summary
Non-lytic: Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).