GeneTex

  • Country / Location Selection

United States (US)

Human IL2 (Superkine) protein, human IgG2 Fc tag (active)

Human IL2 (Superkine) protein, human IgG2 Fc tag (active). GTX65631-pro

Cat. No. GTX65631-pro

Application

 Functional Assay

Species

 Human
Package
10 μg ($419)
See all IL2 superkine protein products

APPLICATION

Application Note

Functional assay: Triggers far greater antitumor responses than native IL-2 in vivo but with lower toxicity.

Product Note

Binds to human and mouse IL-2R.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with 100μl ddH₂O to 0.1mg/ml. Lyophilized from 0.2μm-filtered PBS.

Preservative

No preservative

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.

Region/Sequence

The extracellular domain of human IL-2 superkine (a.a. 21-153) (mutant H9 containing the mutations L80F / R81D / L85V / I 86V / I92F) is fused at the C-terminus to the Fc portion of human IgG2.

Expression System

HEK293 cells

Purity

??95% by SDS-PAGE.

Endotoxin

< 0.01 EU/μg

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interleukin 2 , IL-2 , TCGF , lymphokine

Database

Research Area

DATA IMAGES

Human IL2 (Superkine) protein, human IgG2 Fc tag (active). GTX65631-pro

GTX65631-pro Image

Binding of GTX65631-pro IL2 (Superkine) human Fc fusion protein to IL-2Rβ (human) is increased >10 fold compared to IL-2 human Fc fusion protein. Method: IL-2Rβ (human) protein was coated on an ELISA plate at 1μg/ml. After blocking and washing steps, indicated concentrations of GTX65631-pro IL-2 Superkine (Fc) or IL-2 (Fc) protein were added. Following incubation for 1 h at RT, the binding was detected using an anti-human Fc antibody (HRP).

REFERENCE

There are currently no references for Human IL2 (Superkine) protein, human IgG2 Fc tag (active) (GTX65631-pro). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Human IL2 (Superkine) protein, human IgG2 Fc tag (active) (GTX65631-pro). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Package List Price ($)
$ 419