APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.5 μg/mL |
| 10 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Ramos Cell Lysate(GTX23955) , Jurkat Cell Slide(GTX25533)
Product Note
IRF4 / MUM1 antibody is predicted to not cross-react with other IRF protein family members. IRF4 / MUM1 often migrates at a higher than predicted molecular weight in SDS-PAGE.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
IRF4 / MUM1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human IRF4 / MUM1.The immunogen is located within the last 50 amino acids of IRF4 / MUM1.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
interferon regulatory factor 4 , LSIRF , MUM1 , NF-EM5 , SHEP8
Cellular Localization
Nucleus
Background
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
Database
Research Area
DATA IMAGES
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GTX31438 ICC/IF Image
ICC/IF analysis of Jurkat cells using GTX31438 IRF4 / MUM1 antibody.
Working concentration : 20 μg/ml
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GTX31438 ICC/IF Image
ICC/IF analysis of Jurkat cells using GTX31438 IRF4 / MUM1 antibody.
Working concentration : 10 μg/ml
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GTX31438 WB Image
WB analysis of Ramos cell lysate using GTX31438 IRF4 / MUM1 antibody.
Working concentration : 0.5 μg/ml
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REFERENCE
There are currently no references for IRF4 / MUM1 antibody (GTX31438). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IRF4 / MUM1 antibody (GTX31438). Be the first to share your experience with this product.
