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Insulin antibody [E2E3]

Anti-Insulin antibody [E2E3] used in Immunohistochemistry (IHC). GTX73558
Anti-Insulin antibody [E2E3] used in IHC (Paraffin sections) (IHC-P). GTX73558

Cat. No. GTX73558

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 E2E3

Isotype

 IgG1

Application

 IHC-P, IHC

Reactivity

 Human, Pig
Package
1 ml ($399)
See all Insulin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Swine insulin.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_380250

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10

Cellular Localization

Secreted

Background

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-Insulin antibody [E2E3] used in Immunohistochemistry (IHC). GTX73558

GTX73558 IHC Image

IHC Image using GTX73558 - Detection of Insulin by IHC in Human Pancreas

Anti-Insulin antibody [E2E3] used in IHC (Paraffin sections) (IHC-P). GTX73558

GTX73558 IHC-P Image

Formalin fixed paraffin embedded human pancreas stained with Insulin antibody (cat. # GTX73558).

REFERENCE

Application Reference

O'Brien K et al. PLoS One 2014; 9 (12) : e113956 Identification of the critical therapeutic entity in secreted hsp90α that promotes wound healing in newly re-standardized healthy and diabetic pig models.
Application : IHC
Reactivity : Pig
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399