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Kv1.2 antibody [HL3163]

Recombinant antibody Orthogonal
Anti-Kv1.2 antibody [HL3163] used in Western Blot (WB). GTX640673
Anti-Kv1.2 antibody [HL3163] used in Western Blot (WB). GTX640673

Cat. No. GTX640673

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL3163

Isotype

 IgG

Application

 WB

Reactivity

 Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all Kv1.2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The immunogen used to generate this antibody corresponds to human Kv1.2.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium voltage-gated channel subfamily A member 2 , EIEE32 , HBK5 , HK4 , HUKIV , KV1.2 , MK2 , NGK1 , RBK2

Cellular Localization

Cell membrane,Membrane,Cell projection, axon,Cell junction, synapse,Endoplasmic reticulum membrane,Synapse, synaptosome,Presynaptic cell membrane,Cell projection, dendrite

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Kv1.2 antibody [HL3163] used in Western Blot (WB). GTX640673

GTX640673 WB Image

Orthogonal

Boiled and unboiled rat tissue extract (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Kv1.2 antibody [HL3163] (GTX640673) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Kv1.2 antibody [HL3163] used in Western Blot (WB). GTX640673

GTX640673 WB Image

Orthogonal

Boiled and unboiled mouse tissue extract (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Kv1.2 antibody [HL3163] (GTX640673) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
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Custom Conjugations