LDHA antibody
Cat. No. GTX101416
Cat. No. GTX101416
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HostRabbit
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ClonalityPolyclonal
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IsotypeIgG
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ApplicationsWB ICC/IF IHC-P
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ReactivityHuman, Mouse, Rat
Summary
LDHA facilitates glycolytic flux by converting pyruvate to lactate and NADH to NAD+. It is primarily cytoplasmic, but is also found in mitochondria and the nucleus. In addition to its metabolic function, LDHA is also a single‐stranded DNA‐binding protein participating in DNA duplication and transcription. Elevated expression of LDHA is observed in various cancers.