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MX1 antibody [HMV316] HistoMAX™

Recombinant antibody HistoMAX
Anti-MX1 antibody [HMV316] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639940
Anti-MX1 antibody [HMV316] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639940
Anti-MX1 antibody [HMV316] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639940

Cat. No. GTX639940

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HMV316

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649),
100 μl ($329)
See all MX1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Product Note

This antibody is specific for human MX1 protein, and it does not cross react with human MX2 protein.

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent

Antigen Species

Human

Immunogen

Recombinant fragment of human MX1

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MX dynamin like GTPase 1,IFI-78K,IFI78,MX,MxA

Cellular Localization

Cytoplasm,Endoplasmic reticulum membrane,Cytoplasm,perinuclear region,Nucleus

Background

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Database

Research Area

DATA IMAGES

Anti-MX1 antibody [HMV316] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639940

GTX639940 IHC-P Image

IHC-P analysis of human larynx tissue using GTX639940 MX1 antibody [HMV316] HistoMAX™.
Squamous cell carcinoma with strong MX1 staining of tumor cells. Stromal and inflammatory cells show a less intense MX1 staining.

Anti-MX1 antibody [HMV316] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639940

GTX639940 IHC-P Image

IHC-P analysis of human prostate tissue using GTX639940 MX1 antibody [HMV316] HistoMAX™.
Adenocarcinoma (Gleason 5+5=10) with strong MX1 immunostaining of tumor cells.

Anti-MX1 antibody [HMV316] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639940

GTX639940 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX639940 MX1 antibody [HMV316] HistoMAX™.
Strong cytoplasmic MX1 staining of all epithelial cell types in a sample with some inflammation and scar formation.

REFERENCE

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REVIEW

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Package List Price ($)
$ 649
$ 329
Currently in production