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Melanoma gp100 antibody [MSVA-617R] HistoMAX™

Recombinant antibody HistoMAX
Anti-Melanoma gp100 antibody [MSVA-617R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04382
Anti-Melanoma gp100 antibody [MSVA-617R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04382
Anti-Melanoma gp100 antibody [MSVA-617R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04382

Cat. No. GTX04382

Host

Rabbit

Clonality

Monoclonal

Clone Name

MSVA-617R

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($629),
100 μl ($299)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.

Not tested in other applications.

Calculated MW

70 kDa. ( Note )

Positive Control

Skin: A moderate to strong cytoplasmic PMEL immunostaining should be seen in all melanocytes of the skin.

Negative Control

Colon: PMEL immunostaining should be completely absent in all cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human SILV protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

premelanosome protein , D12S53E , ME20 , ME20-M , ME20M , P1 , P100 , PMEL17 , SI , SIL , SILV , gp100

Cellular Localization

Golgi apparatus , Melanosome

Background

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

Database

Research Area

DATA IMAGES

Anti-Melanoma gp100 antibody [MSVA-617R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04382

GTX04382 IHC-P Image

IHC-P analysis of human malignant melanoma from skin tissue using GTX04382 Melanoma gp100 antibody [MSVA-617R] HistoMAX™.
Strong cytoplasmic melanoma gp100 immunostaining in all cells of a malignant melanoma of the skin.

Anti-Melanoma gp100 antibody [MSVA-617R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04382

GTX04382 IHC-P Image

IHC-P analysis of human mucosa from rectum tissue using GTX04382 Melanoma gp100 antibody [MSVA-617R] HistoMAX™.

Anti-Melanoma gp100 antibody [MSVA-617R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04382

GTX04382 IHC-P Image

IHC-P analysis of human skin tissue using GTX04382 Melanoma gp100 antibody [MSVA-617R] HistoMAX™.
Strong melanoma gp100 immunostaining in melanocytes of the skin.

REFERENCE

There are currently no references for Melanoma gp100 antibody [MSVA-617R] HistoMAX™ (GTX04382). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Melanoma gp100 antibody [MSVA-617R] HistoMAX™ (GTX04382). Be the first to share your experience with this product.
Package List Price ($)
$ 629
$ 299