APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500~1:1000 |
1:100~1:500 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human NECAB3 (321-370).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
APBA2BP , EFCBP3 , NECAB3 , NIP1 , Nterminal EFhand calcium binding protein 3 , STIP3 , SYTIP2 , XB51 , dJ63M2.4 , dJ63M2.5 , N-terminal EF-hand calcium binding protein 3
Cellular Localization
Golgi apparatus
Background
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX87171 WB Image
WB analysis of HepG2, COLO, and HT-29 cell lysates using GTX87171 NECAB3 antibody. The lane on the right is blocked with the synthesized peptide.
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GTX87171 ICC/IF Image
ICC/IF analysis of A549 cells using GTX87171 NECAB3 antibody. The picture on the right is blocked with the synthesized peptide.
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REFERENCE
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REVIEW
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