APPLICATION
Product Note
The peptide was used in the production of GTX89500.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-ETDDQSPEKIN
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Sodium Voltage-Gated Channel Alpha Subunit 5 , Cdcd2 , Cmd1E , Cmpd2 , Hb1 , Hb2 , Hbbd , Hh1 , Iccd , Ivf , Lqt3 , Nav1.5 , Pfhb1 , Sss1 , Vf1 , Scn5A
Background
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Research Area
REFERENCE
There are currently no references for Nav1.5 blocking peptide (GTX89500-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Nav1.5 blocking peptide (GTX89500-PEP). Be the first to share your experience with this product.