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PARP antibody

KO/KD Comparison Orthogonal Overexpression
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in ChIP assay (ChIP assay). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in IHC (Paraffin sections) (IHC-P). GTX100573
Anti-PARP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Western Blot (WB). GTX100573
Anti-PARP antibody used in Immunoprecipitation (IP). GTX100573
Anti-PARP antibody used in ChIP assay (ChIP assay). GTX100573

Cat. No. GTX100573

Reference 80
2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP, ChIP assay

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all PARP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
IP Assay dependent
ChIP assay Assay dependent
Not tested in other applications.

Calculated MW

113 kDa. ( Note )

Positive Control

HCT116 (30uM cisplatin treatment for 24hr) , PC-12 , Rat2 , 293T , A431 , HeLa , HepG2

Product Note

This antibody is specific for human PARP1 protein, and it does not cross react with human PARP2 and PARP3 protein.

Predict Reactivity

Bovine, Chicken(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.3 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human PARP1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1241155

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

poly(ADP-ribose) polymerase 1 , ADPRT , ADPRT 1 , ADPRT1 , ARTD1 , PARP , PARP-1 , PPOL , pADPRT-1

Cellular Localization

Nucleus,Nucleolus

Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

KO/KD

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody (GTX100573) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

PARP1 antibody detects PARP1 protein by western blot analysis.
A. 30 μg HCT116 whole cell lysate/extract (untreated)
B. 30 μg HCT116 whole cell lysate/extract (30 μM cisplatin treatment for 24hr)
7.5% SDS-PAGE
PARP1 antibody (GTX100573) dilution: 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Comparison

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membranes were blotted with PARP antibody (GTX100573) diluted at 1:2000 and competitor's antibody (#9542) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with PARP antibody (GTX100573) diluted at 1:2000.

Anti-PARP antibody used in ChIP assay (ChIP assay). GTX100573

GTX100573 ChIP assay Image

Cross-linked ChIP was performed with Raji chromatin extract and 5 μg of either control rabbit IgG or anti-PARP1 antibody. The precipitated DNA was detected by PCR with primer set targeting to S100A9 promoter.
ChIP experiment and primer designs are based on BMC Mol Biol. 2006 Dec 22;7:48.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Overexpression

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody (GTX100573) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PARP antibody used in IHC (Paraffin sections) (IHC-P). GTX100573

GTX100573 IHC-P Image

PARP antibody detects PARP protein at nucleus in human oral carcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded human oral carcinoma.
PARP antibody (GTX100573) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-PARP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100573

GTX100573 ICC/IF Image

PARP antibody detects PARP protein at nucleus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: PARP protein stained by PARP antibody (GTX100573) diluted at 1:500.
Red: Phalloidin, a cytoskeleton marker, diluted at 1:100.
Scale bar = 10 μm.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Overexpression

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody (GTX100573) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with PARP antibody (GTX100573) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

Untreated (–) and treated (+) HeLa whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody (GTX100573) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the journal Sci Rep in 2017.PMID: 28928421

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the journal Nat Commun in 2016.PMID: 27703167

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the 2022 in Cancers (Basel). PMID: 35008409

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the 2022 in FEBS Open Bio. PMID: 34856073

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the journal Oncotarget in 2016. PMID: 26716417

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the journal PLoS Genet in 2016. PMID: 27626929

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

KO/KD

The data was published in the journal PLoS Genet in 2016. PMID: 27626929

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the journal Evid Based Complement Alternat Med in 2012. PMID: 23091557

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the journal PLoS Genet in 2016. PMID: 27626929

Anti-PARP antibody used in Western Blot (WB). GTX100573

GTX100573 WB Image

Orthogonal

The data was published in the journal Oncotarget in 2015. PMID: 26160843

Anti-PARP antibody used in Immunoprecipitation (IP). GTX100573

GTX100573 IP Image

The data was published in the journal Nat Commun in 2016.PMID: 27703167

Anti-PARP antibody used in ChIP assay (ChIP assay). GTX100573

GTX100573 ChIP assay Image

The data was published in the journal PLoS Genet in 2016. PMID: 27626929

REFERENCE

Application Reference

Zhou B et al. Chin Med 2023; 18 (1) : 139 Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD(2)-HO-1 signal axis.
Chang HA et al. Cell Death Discov 2023; 9 (1) : 385 YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions.
B Zhou et al. Chinese Medicine 2023; 18 : 139 Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD2-HO-1 signal axis
Wang J et al. Exp Ther Med 2023; 26 (2) : 407 Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis.
E Fletcher et al. Transl Res 2023; S1931-5244 (23) : 00088-9 Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease
Application : WB
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Submit a Reference

REVIEW

PARP antibody Cat. No. GTX100573

Rating
( Average 5 based on 2 users reviews)
Application
Western Blot(WB)
( Average 5 based on 2 users reviews)
Anti-PARP antibody used in Western Blot (WB). GTX100573
Date : Anonymous submitted on 31-Jan-2021
Score :
Application Tested : WB
Sample Species : Hu
Sample : iPSC
Amount used : 25 μg
Blocking : 5% milk, 25°C, 1Hr
Primary Antibody : 1:1000, 4°C, 16Hr
Anti-PARP antibody used in Western Blot (WB). GTX100573
Date : Anonymous submitted on 26-May-2018
Score :
Application Tested : WB
Sample Species : Hu
Sample : MG63 cells
Amount used : 30 μg
Primary Antibody : 1:1000, 4°C, 16Hr
Lane Description : Lane 1: Untreated MG63 whole cell lysate, Lane 2: Treated (IOX-1; 3uM) MG63 whole cell lysate, Lane 3: Treated (IOX-1; 10uM) MG63 whole cell lysate
Submit a Review
Application Reference
Zhou B et al. Chin Med 2023; 18 (1):139 Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD(2)-HO-1 signal axis.
Chang HA et al. Cell Death Discov 2023; 9 (1):385 YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions.
B Zhou et al. Chinese Medicine 2023; 18:139 Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD2-HO-1 signal axis
Wang J et al. Exp Ther Med 2023; 26 (2):407 Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis.
E Fletcher et al. Transl Res 2023; S1931-5244 (23):00088-9 Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease
Application : WB
Huang C et al. Pharmaceuticals (Basel) 2023; 16 (5) α-Viniferin-Induced Apoptosis through Downregulation of SIRT1 in Non-Small Cell Lung Cancer Cells.
Calcagno G et al. Int J Mol Sci 2022; 23 (13) Chronic Hypergravity Induces a Modification of Histone H3 Lysine 27 Trimethylation at TCRβ Locus in Murine Thymocytes.
Application : WB
Reactivity : Mouse
Wu DD et al. iScience 2022; 25 (12):105459
Sonia Brun et al. Autophagy 2022; 18 (3):678-694 GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions.
Application : WB
Reactivity : Human
Vichuda Charoensaensuk et al. Antioxidants (Basel) 2022; 11 (4) 2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside Attenuates Reactive Oxygen Species-Dependent Inflammation and Apoptosis in Porphyromonas gingivalis-Infected Brain Endothelial Cells.
Application : WB
Chiang-Wen Lee et al. Molecules 2022; 27 (2) Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines.
Application : WB
Reactivity : Human
Yongfeng Zhou et al. FEBS Open Bio 2022; 12 (2):379-393 Integrative investigation of the TF-miRNA coregulatory network involved in the inhibition of breast cancer cell proliferation by resveratrol.
Application : WB
Reactivity : Human
Lu-Yun Qin et al. Front Pharmacol 2022; 13:812594 Therapeutic Potential of Astragaloside IV Against Adriamycin-Induced Renal Damage in Rats via Ferroptosis.
Application : WB
Lin CH et al. Cancers (Basel) 2022; 14 (1) Comparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness.
Application : WB
Reactivity : Human
Lin TE et al. J Enzyme Inhib Med Chem 2022; 37 (1):226-235 Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors.
Application : WB
Reactivity : Human
Lee CW et al. Molecules 2022; 27 (2):373 Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines.
Application : WB
Reactivity : Human
Tang YC et al. J Food Drug Anal 2021; 29 (4):638-652 A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells.
Application : WB
Reactivity : Human
Kuo-Hao Ho et al. Neurotherapeutics 2021; 18 (2):1371-1392 Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling.
Application : WB
Reactivity : Human
Shiau-Mei Chen et al. Biomolecules 2021; 11 (10) Activation of Aldehyde Dehydrogenase 2 Ameliorates Glucolipotoxicity of Pancreatic Beta Cells.
Application : WB
Reactivity : Mouse
Charoensaensuk V et al. Cells 2021; 10 (11) Porphyromonas gingivalis Induces Proinflammatory Cytokine Expression Leading to Apoptotic Death through the Oxidative Stress/NF-κB Pathway in Brain Endothelial Cells.
Application : WB
Reactivity : Mouse
Machour FE et al. Nucleic Acids Res 2021; 49 (20):11708-11727 RBM6 splicing factor promotes homologous recombination repair of double-strand breaks and modulates sensitivity to chemotherapeutic drugs.
Yang JL et al. In Vivo 2021; 35 (5):2687-2696 Ouabain Induces DNA Damage in Human Osteosarcoma U-2 OS Cells and Alters the Expression of DNA Damage and DNA Repair-associated Proteins.
Application : WB
Inturi R. et al. Virology 2021; 562:92-102 CRISPR/Cas9-based inactivation of human papillomavirus oncogenes E6 or E7 induces senescence in cervical cancer cells.
Application : WB
Reactivity : Human
Luo LF et al. Front Pharmacol 2021; 12:669782 Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy.
Application : WB
Reactivity : Rat
Li Y et al. Transl Lung Cancer Res 2021; 10 (4):1841-1856 Let-7b-3p inhibits tumor growth and metastasis by targeting the BRF2-mediated MAPK/ERK pathway in human lung adenocarcinoma.
Application : WB
Reactivity : Human
Cha Y.E. et al. Int. J. Mol. Sci. 2021; 22 (6):2947 6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway.
Application : WB
Reactivity : Human
Hsu WH et al. Aging (Albany NY) 2020; 12 (11):10556-10577 T1-11, an adenosine derivative, ameliorates aging-related behavioral physiology and senescence markers in aging mice.
Application : WB
Reactivity : Human
Hsieh PF et al. Cancers (Basel) 2020; 12 (4) Emerging Therapeutic Activity of Davallia formosana on Prostate Cancer Cells through Coordinated Blockade of Lipogenesis and Androgen Receptor Expression.
Application : WB
Reactivity : Human
An JR et al. Life Sci 2020; 250:117573 Huperzine A, reduces brain iron overload and alleviates cognitive deficit in mice exposed to chronic intermittent hypoxia.
Application : WB
Reactivity : Mouse
Lin MW et al. Neurotherapeutics 2019; (Epub) Galantamine Inhibits Aβ1-42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1-42 Engulfment During Autophagic Degradation.
Application : WB
Reactivity : Human
van Gastel J et al. Aging (Albany NY) 2019; 11 (23):11268-11313 The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage.
Application : WB
Reactivity : Human
Takino JI et al. Sci Rep 2019; 9 (1):16717 The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells.
Application : WB
Reactivity : Human
Tsai CH et al. Biochim Biophys Acta Mol Cell Res 2019; 1867 (2):118564 Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKC帢-mediated AHR-HDAC interactions.
Application : WB
Reactivity : Human
Wei GJ et al. AAPS J 2019; 21 (5):86 A Tangeretin Derivative Inhibits the Growth of Human Prostate Cancer LNCaP Cells by Epigenetically Restoring p21 Gene Expression and Inhibiting Cancer Stem-like Cell Proliferation.
Application : WB
Reactivity : Human
Huang SY et al. Prostate 2019; (Epub) Osajin displays potential antiprostate cancer efficacy via impairment of fatty acid synthase and androgen receptor expression.
Application : WB
Reactivity : Human
Bera R et al. Neoplasia 2018; 20 (11):1106-1120 Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells.
Lee CW et al. J Cell Physiol 2018; (Epub) Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species.
Application : WB
Reactivity : Human
Huang MH et al. Pharmacol Res 2018; 139:50-61 Epigenetic targeting DNMT1 of pancreatic ductal adenocarcinoma using interstitial control release biodegrading polymer reduced tumor growth through hedgehog pathway inhibition.
Application : WB
Reactivity : Human
Huang S.Y. et al. Molecules 2018; 23 (10):2539 Ganoderma tsugae Inhibits the SREBP-1/AR Axis Leading to Suppression of Cell Growth and Activation of Apoptosis in Prostate Cancer Cells.
Application : WB
Reactivity : Human
Li Y et al. Nanomedicine (Lond) 2018; (Epub) Dual targeting delivery of miR-328 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy.
Application : WB
Reactivity : Human
Kim J.Y. et al. Hindawi 2018; (Epub) Annona muricata leaf extract triggered intrinsic apoptotic pathway to attenuate cancerous features of triple negative breast cancer MDA-MB-231 cells.
Application : WB
Reactivity : Human
Dominguez G et al. Acta Neuropathol Commun 2018; 6 (1):25 Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain.
Application : WB
Reactivity : Human
Chen PY et al. Int J Mol Sci 2018; 19 (4) Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein.
Application : WB
Reactivity : Human
Chang HP et al. Int J Oncol 2018; (Epub) pterostilbene modulates the suppression of multidrug resistance protein-1 and triggers autophagic and apoptotic mechanisms in *-resistant human oral cancer car cells via akt signaling.
Application : WB
Reactivity : Human
Lin YC et al. Journal of Functional Foods 2018; 42:75-84 Luteolin inhibits ER-α expression through ILK inhibition is regulated by a pathway involving Twist and YB-1.
Lin SC et al. Oncol Rep 2018; 39 (2):703-710 Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway.
Application : WB
Liang X et al. Br J Cancer 2017; 116 (7):903-911 Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells.
Ghasemi F et al. Oncotarget 2017; 8 (42):71512-71519 Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer.
Lee WY et al. Int J Cancer 2017; 141 (9):1921-1931 * sensitizes kras-mutant non-small-cell lung cancer to * by targeting taz.
Application : WB
Reactivity : Human
Li SM et al. Sci Rep 2017; 7 (1):11893 Upregulation of CISD2 augments ROS homeostasis and contributes to tumorigenesis and poor prognosis of lung adenocarcinoma.
Application : WB
Reactivity : Human
Hsieh MH et al. Nucleic Acids Research 2017; (Epub) PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells.
Application : WB
Reactivity : Human
Tsui KH et al. Reproduction 2017; 154 (2):101-110 DHEA protects mitochondria against dual modes of apoptosis and necroptosis in human granulosa HO23 cells.
Application : WB
Reactivity : Human
Lee CC et al. PLoS One 2017; 12 (3):e0173890 the microrna-302b-inhibited *-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor ia.
Application : WB
Reactivity : Human
Xu YM et al. Oncotarget 2016; 7 (5):6146-58 Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells.
Application : WB
Reactivity : Human
Chen PH et al. PLoS One 2016; 11 (11):e0167096 the inhibition of microrna-128 on igf-1-activating mtor signaling involves in *-induced glioma cell apoptotic death.
Application : WB
Reactivity : Human
Zheng Y et al. Int J Biol Sci 2016; 12 (1):120-32 Photodynamic-therapy Activates Immune Response by disrupting Immunity Homeostasis of Tumor Cells, which Generates Vaccine for Cancer Therapy.
Application : WB
Reactivity : Mouse
Chakraborty A et al. Nat Commun 2016; 7:13049 Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes.
Application : IP
Reactivity : Human
Li G et al. PLoS Genet 2016; 12 (9):e1006292 The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1.
Application : ChIP assay
Reactivity : Human
Su TJ et al. Am J Cancer Res 2016; 6 (6):1317-30 oncogenic mir-137 contributes to * resistance via repressing casp3 in lung adenocarcinoma.
Application : WB
Reactivity : Human
Chen PH et al. Neuropharmacology 2016; 110 (Pt A):362-75 The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death.
Application : WB
Reactivity : Human
Shindo Y et al. Sci Rep 2016; 6:29224 An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation.
Application : WB
Reactivity : Human
Yuanhong Zheng et al. International Journal of Biological Sciences 2016; 12 (1):120-132 Photodynamic-therapy Activates Immune Response by disrupting Immunity Homeostasis of Tumor Cells, which Generates Vaccine for Cancer Therapy.
Application : WB
Reactivity : Mouse
Yong WK et al. Evid Based Complement Alternat Med 2015; 2015:921306 Xanthohumol induces growth inhibition and apoptosis in ca ski human cervical cancer cells.
Application : WB
Reactivity : Human
Chou SF et al. PLoS Pathog 2015; 11 (10):e1005123 The Dual Role of an ESCRT-0 Component HGS in HBV Transcription and Naked Capsid Secretion.
Application : WB
Reactivity : Human
Yang SH et al. Oncotarget 2015; 6 (27):23857-73 lovastatin overcomes * resistance through tnf-α signaling in human cholangiocarcinomas with different lkb1 statuses in vitro and in vivo.
Ruan Y et al. Mol Med Rep 2015; 12 (4):5796-806 Autophagy inhibition enhances isorhamnetin-induced mitochondria-dependent apoptosis in non-small cell lung cancer cells.
Lee WY et al. Oncotarget 2015; (Epub) repositioning antipsychotic * for treating colorectal cancer by inhibiting sirtuin 1.
Application : WB
Reactivity : Human
Li CJ et al. Sci Rep 2015; (Epub) Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis.
Application : WB
Reactivity : Human
Yang DJ et al. J Food Biochem 2015; 39 (3):334-343 Three Pathways Assess Anti-Inflammatory Response of Epicatechin with Lipopolysaccharide-Mediated Macrophage RAW264.7 Cells.
Application : WB
Reactivity : Mouse
Huang RF et al. Int J Nanomedicine 2015; 10:2823-46 Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene.
Application : WB
Reactivity : Human
Szu-Ting Lin et al. Cellular and Molecular Life Sciences 2015; 72 (12):2395-409 pgrmc1 contributes to *-induced chemoresistance in mes-sa uterine sarcoma.
Application : WB
Reactivity : Human
Zheng J et al. Br J Cancer 2014; 110 (8):2116-22 Biliverdin's regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer.
Application : WB
Reactivity : Human
Chin YT et al. Oncotarget 2014; 5 (24):12891-907 Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro.
Application : WB
Reactivity : Human
Chen PH et al. J Neurochem 2014; MicroRNA-302b-inhibited E2F3 transcription factor is related to all trans retinoic acid-induced glioma cell apoptosis.
Application : WB
Reactivity : Human
Li KC et al. Mol Cancer 2014; 13:172 Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma.
Application : WB
Reactivity : Human
Yang DJ et al. J Agric Food Chem 2014; 62 (15):3458-65 Inhibitory effect of litchi (Litchi chinensis Sonn.) flower on lipopolysaccharide-induced expression of proinflammatory mediators in RAW264.7 cells through NF-κB, ERK, and JAK2/STAT3 inactivation.
Application : WB
Reactivity : Mouse
Lin MH et al. Chem Biol Interact 2014; 218C:42-49 Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells.
Application : WB
Reactivity : Human
Li CJ et al. Evid Based Complement Alternat Med 2012; 2012:261971 Momordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways.
Application : WB
Reactivity : Human
Liu CH et al. J Ethnopharmacol 2011; 137 (1):503-11 Subamolide A, a component isolated from Cinnamomum subavenium, induces apoptosis mediated by mitochondria-dependent, p53 and ERK1/2 pathways in human urothelial carcinoma cell line NTUB1.
Application : WB
Reactivity : Human
Zhao J et al. J Proteomics 2011; 75 (2):588-602 Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF).
Application : WB
Reactivity : Human
SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf
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