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RPSA antibody [RPSA/2699]

Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349
Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349
Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349
Anti-RPSA antibody [RPSA/2699] used in  (). GTX04349
Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349
Anti-RPSA antibody [RPSA/2699] used in Protein Array (Protein Array). GTX04349
Anti-RPSA antibody [RPSA/2699] used in Flow cytometry (FACS). GTX04349
Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349
Anti-RPSA antibody [RPSA/2699] used in Western Blot (WB). GTX04349
Anti-RPSA antibody [RPSA/2699] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04349
Anti-RPSA antibody [RPSA/2699] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04349

Cat. No. GTX04349

Host

Mouse

Clonality

Monoclonal

Clone Name

RPSA/2699

Isotype

IgG1

Application

WB, ICC/IF, IHC-P, FACS, Protein Array

Reactivity

Human
Package
100 μg ($529)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
ICC/IF 1-2 μg/ml
IHC-P 1-2 μg/ml
FACS 1-2 μg/ml
Protein Array Assay dependent

Note :

IHC-P
heating tissue sections in 10mM Tris with 1mM EDTA (pH 9.0)

Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-lengthhuman RPSA protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ICAS,LAMBR,LAMR1,LBP,LBP/p40,LRP,LRP/LR,NEM/1CHD4,RPSA,SA,lamR,p40,ribosomal protein SA,37LRP,67LR,67kDa Laminin Receptor

Cellular Localization

Cell membrane,Cytoplasm,Nucleus

Background

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349

GTX04349 IHC-P Image

IHC-P analysis of human basal cell carcinoma tissue using GTX04349 RPSA antibody [RPSA/2699].

Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349

GTX04349 IHC-P Image

IHC-P analysis of human cervical carcinoma tissue using GTX04349 RPSA antibody [RPSA/2699].

Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349

GTX04349 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX04349 RPSA antibody [RPSA/2699].

Anti-RPSA antibody [RPSA/2699] used in  (). GTX04349

GTX04349 Image

SDS-PAGE of GTX04349 RPSA antibody [RPSA/2699].

Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349

GTX04349 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX04349 RPSA antibody [RPSA/2699].

Anti-RPSA antibody [RPSA/2699] used in Protein Array (Protein Array). GTX04349

GTX04349 Protein Array Image

Analysis of Protein Array containing >19,000 full-length human proteins using GTX04349 RPSA antibody [RPSA/2699]. Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Anti-RPSA antibody [RPSA/2699] used in Flow cytometry (FACS). GTX04349

GTX04349 FACS Image

FACS analysis of PFA-fixed Raji cells using GTX04349 RPSA antibody [RPSA/2699].
Blue : Primary antibody
Red : Isotype control

Anti-RPSA antibody [RPSA/2699] used in IHC (Paraffin sections) (IHC-P). GTX04349

GTX04349 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX04349 RPSA antibody [RPSA/2699].

Anti-RPSA antibody [RPSA/2699] used in Western Blot (WB). GTX04349

GTX04349 WB Image

WB analysis of various sample lysates using GTX04349 RPSA antibody [RPSA/2699].

Anti-RPSA antibody [RPSA/2699] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04349

GTX04349 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX04349 RPSA antibody [RPSA/2699].
Green : Primary antibody
Red : Nuclei

Anti-RPSA antibody [RPSA/2699] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04349

GTX04349 ICC/IF Image

ICC/IF analysis of PFA-fixed Raji cells using GTX04349 RPSA antibody [RPSA/2699].
Green : Primary antibody
Red : Nuclei

REFERENCE

There are currently no references for RPSA antibody [RPSA/2699] (GTX04349). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for RPSA antibody [RPSA/2699] (GTX04349). Be the first to share your experience with this product.
Package List Price ($)
$ 529