SOX2 antibody [N1C3]

Name: SOX2 antibody [N1C3]
Brand: GeneTex
SKU: GTX101507
Price: 399.00 USD
Rating: 3 (1 reviews)

Anti-SOX2 antibody [N1C3] used in Western Blot (WB). GTX101507

Anti-SOX2 antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX101507

Anti-SOX2 antibody [N1C3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX101507

Anti-SOX2 antibody [N1C3] used in IHC (Frozen sections) (IHC-Fr). GTX101507

Anti-SOX2 antibody [N1C3] used in Flow cytometry (FACS). GTX101507

Anti-SOX2 antibody [N1C3] used in Immunoprecipitation (IP). GTX101507

Cat. No. GTX101507

Reference 69

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP
Reactivity	Human, Mouse, Rat, Frog, Ceratotherium simum
Package	100 μl ($399), 25 μl ($169)

See all SOX2 products

View product citations for antibody GTX101507 on CiteAb

PRODUCT

Summary

SOX2 antibody detects SOX2 protein, a basic helix-loop-helix transcription factor (predicted molecular weight of 34 kDa). SOX2 is an indispensable factor for regulating embryonic development and in the generation of inducible pluripotent stem (iPS) cells. It is also expressed in neural stem and progenitor cells. Dysregulation of SOX2 is associated with tumorigenesis.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:5000-1:20000
ICC/IF	1:100-1:1000
IHC-P	1:100-1:1000
IHC-Fr	1:100-1:1000
FACS	1:50-1:200
IP	1:100-1:500

Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Positive Control

Mouse ESC , hESC , NT2D1 , NT2D1

Predict Reactivity

Zebrafish, Sheep, Bovine, Cat, Chicken, Pig, Japanese Medaka, Xenopus tropicalis, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.15 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2038021

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SRY-box 2 , ANOP3 , MCOPS3

Cellular Localization

Nucleus

Background

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]

Database

Gene ID: 6657 SOX2
UniProt: P48431 SOX2

Research Area

DATA IMAGES

GTX101507 WB Image

Non-transfected (–) and transfected (+) NT2D1 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with SOX2 antibody [N1C3] (GTX101507) diluted at 1:15000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101507 IHC-P Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus in mouse esophagus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse esophagus.
SOX2 antibody [N1C3] (GTX101507) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101507 WB Image

Whole cell extract (30 μg) was separated by 12% SDS-PAGE, and the membranes were blotted with SOX2 antibody [N1C3] (GTX101507) diluted at 1:10000 and competitor's antibody (sc-17320) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

GTX101507 WB Image

Whole cell extract (30 μg) was separated by 12% SDS-PAGE, and the membranes were blotted with SOX2 antibody [N1C3] (GTX101507) diluted at 1:1000 and competitor's antibody (sc-17320) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

GTX101507 ICC/IF Image

Immunofluorescence analysis of paraformaldehyde-fixed Human ESC, using SOX2(GTX101507) antibody at 1:160 dilution.

GTX101507 IHC-Fr Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus by immunohistochemical analysis.
Sample: Frozen sectioned E13.5 rat brain.
Green: SOX2 protein stained by SOX2 antibody [N1C3] (GTX101507) diluted at 1:250.
Red: beta Tubulin 3/ TUJ1, a mature neuron marker, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] (GTX631836) diluted at 1:250.
Blue: Fluoroshield with DAPI (GTX30920).

GTX101507 IHC-Fr Image

SOX2 antibody [N1C3] detects SOX2 protein expression by immunohistochemical analysis.
Sample: Frozen-sectioned adult mouse hippocampus.
Green: SOX2 protein stained by SOX2 antibody [N1C3] (GTX101507) diluted at 1:250.
Blue: Fluoroshield with DAPI (GTX30920).

GTX101507 ICC/IF Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus by immunofluorescent analysis.
Sample: NT2D1 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: SOX2 stained by SOX2 antibody [N1C3] (GTX101507) diluted at 1:500.
Red: phalloidin, a cytoskeleton marker, diluted at 1:100.
Scale bar= 10 μm.

GTX101507 FACS Image

Flow cytometry on human embryonic stem cells, staining with SOX2 (GTX101507)antibody at 1:100 dilution(purple) or rabbit IgG (black).

GTX101507 IHC-P Image

Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using SOX2(GTX101507) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX101507 WB Image

SOX2 antibody detects SOX2 protein by Western blot analysis. Whole cell extracts (30 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with SOX2 antibody (GTX101507) at a dilution of 1:2500.

GTX101507 IHC-P Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus on rat brain stem by immunohistochemical analysis.
Sample: Paraffin-embedded rat brain stem.
SOX2 antibody [N1C3] (GTX101507) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX101507 WB Image

Whole cell extract (30 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with SOX2 antibody [N1C3] (GTX101507) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101507 IHC-P Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus in human cervical carcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded human cervical carcinoma.
SOX2 antibody [N1C3] (GTX101507) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101507 IP Image

Immunoprecipitation of SOX2 protein from NT2D1 whole cell extracts using 5 μg of SOX2 antibody [N1C3] (GTX101507) or SOX2 antibody [GT1876] (GTX627404).
Western blot analysis was performed using SOX2 antibody [N1C3] (GTX101507) diluted at 1:500.
EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.

GTX101507 IP Image

Immunoprecipitation of SOX2 protein from NT2D1 whole cell extracts using 5 μg of SOX2 antibody [N1C3] (GTX101507).
Western blot analysis was performed using SOX2 antibody [N1C3] (GTX101507).
EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.

GTX101507 WB Image

SOX2 antibody detects SOX2 protein by western blot analysis. Mouse ESC lysate (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with SOX2 antibody (GTX101507) at a dilution of 1:2500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101507 IHC-Fr Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus by immunohistochemical analysis.
Sample: Frozen sectioned adult mouse retina.
Green: SOX2 protein stained by SOX2 antibody [N1C3] (GTX101507) diluted at 1:250.
Red: Protein kinase C alpha staining.
Blue: Fluoroshield with DAPI (GTX30920).

GTX101507 ICC/IF Image

Immunofluorescence analysis of paraformaldehyde-fixed mouse ESC, using SOX2(GTX101507) antibody at 1:80 dilution.

GTX101507 IHC-P Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus in mouse fetal brain by immunohistochemical analysis.
Sample: Paraffin-embedded mouse fetal brain.
Green: SOX2 antibody [N1C3] (GTX101507) diluted at 1:200. The signal was developed using goat anti-rabbit IgG antibody (Dylight488) (GTX213110-04).
Blue: Nuclear staining with Hoechst 33342.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101507 IHC-P Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded human esophageal carcinoma.
SOX2 stained by SOX2 antibody [N1C3] (GTX101507) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101507 IHC-P Image

SOX2 antibody [N1C3] detects SOX2 protein at nucleus on mouse fore brain by immunohistochemical analysis.
Sample: Paraffin-embedded mouse fore brain.
SOX2 antibody [N1C3] (GTX101507) diluted at 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX101507 WB Image

The data was published in the journal Elife in 2017.PMID: 28537559

GTX101507 WB Image

The data was published in the journal J Cancer in 2020.PMID: 32201526

GTX101507 ICC/IF Image

The data was published in the journal J Cancer in 2020.PMID: 32201526

GTX101507 WB Image

The data was published in the journal Sci Rep in 2016.PMID: 27226076

GTX101507 IHC-P Image

The data was published in the journal Neural Plast in 2016.PMID: 28018679

GTX101507 IHC-P Image

The data was published in the journal Neural Plast in 2016.PMID: 28018679

GTX101507 WB Image

The data was published in the journal Elife in 2017.PMID: 28537559

GTX101507 IHC-Fr Image

The data was published in the journal Dis Model Mech in 2018.PMID: 29208635

GTX101507 ICC/IF Image

The data was published in the journal PLoS One in 2016. PMID: 27802323

GTX101507 WB Image

The data was published in the journal Stem Cell Res Ther in 2013. PMID: 24423398

GTX101507 ICC/IF Image

The data was published in the journal Nat Commun in 2018. PMID: 29973581

REFERENCE

Application Reference

Li H et al. Sci Adv 2024; 10 (2) : eadk4741 Silencing dentate newborn neurons alters excitatory/inhibitory balance and impairs behavioral inhibition and flexibility.

Liu S et al. Neural Regen Res 2024; 19 (2) : 440-446 Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.

Li CJ et al. Front Cell Dev Biol 2023; 11 : 1331584 Generation of induced pluripotent stem cells from Bornean orangutans.

YF Tsai et al. Cancer Cell Int 2023; RAD51 is a poor prognostic marker and a potential therapeutic target for oral squamous cell carcinoma

Application : WB

Wang CH et al. Regen Ther 2023; 24 : 443-450 Cbx7 promotes the generation of induced pluripotent stem cells.

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Submit a Reference

REVIEW

SOX2 antibody [N1C3] Cat. No. GTX101507

Rating

( Average 3 based on 1 users reviews)

Application

Western Blot(WB)

( Average 3 based on 1 users reviews)

Date : Anonymous submitted on 18-Jul-2016

Score :

Application Tested : WB

Sample Species : Hu

Sample : A549 cells, T24 cells

Amount used : 1* 10^5 cells

Blocking : 5% milk, 25°C, 1Hr

Primary Antibody : 1:1000, 4°C, 16Hr

Lane Description : Lane 1: A549 cells, Lane 2: T24 cells.

Submit a Review

Application Reference

Li H et al. Sci Adv 2024; 10 (2):eadk4741 Silencing dentate newborn neurons alters excitatory/inhibitory balance and impairs behavioral inhibition and flexibility.

Liu S et al. Neural Regen Res 2024; 19 (2):440-446 Transplantation of fibrin-thrombin encapsulated human induced neural stem cells promotes functional recovery of spinal cord injury rats through modulation of the microenvironment.

Li CJ et al. Front Cell Dev Biol 2023; 11:1331584 Generation of induced pluripotent stem cells from Bornean orangutans.

YF Tsai et al. Cancer Cell Int 2023; RAD51 is a poor prognostic marker and a potential therapeutic target for oral squamous cell carcinoma

Application : WB

Wang CH et al. Regen Ther 2023; 24:443-450 Cbx7 promotes the generation of induced pluripotent stem cells.

CH Wang et al. Regen Ther 2023; 24:443-450 Cbx7 promotes the generation of induced pluripotent stem cells

Application : ICC/IF

Cuevas-Oca?a S et al. Int J Mol Sci 2023; 24 (12) A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells.

Chen A et al. Front Mol Neurosci 2023; 16:1151162

Jin C et al. Bioeng Transl Med 2023; 8 (2):e10448 Spinal cord tissue engineering using human primary neural progenitor cells and astrocytes.

Application : ICC/IF

Reactivity : Human

Calatayud-Baselga I et al. Nat Commun 2023; 14 (1):7541 Autophagy drives the conversion of developmental neural stem cells to the adult quiescent state.

Mohankumar K et al. Mol Carcinog 2022; 61 (1):73-84 Nuclear receptor 4A1 (NR4A1) antagonists target paraspeckle component 1 (PSPC1) in cancer cells.

Application : WB

Reactivity : Human

Masola V et al. Front Oncol 2022; 12:918419 Heparanase regulates EMT and cancer stem cell properties in prostate tumors.

Application : WB

Reactivity : Human

Peng Ye et al. Biomolecules 2022; 12 (5) Alanine-Glyoxylate Aminotransferase Sustains Cancer Stemness Properties through the Upregulation of SOX2 and OCT4 in Hepatocellular Carcinoma Cells.

Application : WB

Reactivity : Human

Elisa De Tomi et al. Int J Mol Sci 2022; 23 (3) Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins.

Application : WB

Reactivity : Human

Wei-Fang Chang et al. Int J Mol Sci 2021; 22 (2) Effects of Survival Motor Neuron Protein on Germ Cell Development in Mouse and Human.

Application : ICC/IF

Reactivity : Human

Cristina Mir et al. Cancers (Basel) 2021; 13 (19) SDCBP Modulates Stemness and Chemoresistance in Head and Neck Squamous Cell Carcinoma through Src Activation.

Application : WB

Reactivity : Human

Gupta A et al. Life (Basel) 2021; 11 (12) Activation of the Hippo Pathway in Rana sylvatica: Yapping Stops in Response to Anoxia.

Application : WB

Reactivity : Frog

Ting HC et al. Cells 2021; 10 (10) Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.

Application : ICC/IF

Reactivity : Human

Wang SM et al. Cell Death Discov 2021; 7 (1):8 CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma.

Application : WB

Reactivity : Human

Carelli S et al. Nanotheranostics 2021; 5 (1):8-26 Neural precursors cells expanded in a 3D micro-engineered niche present enhanced therapeutic efficacy in vivo.

Application : WB

Reactivity : Mouse

Tsai LH et al. Sci Rep 2020; 10 (1):17817

Application : WB

Reactivity : Human

Chu EP et al. Stem Cell Res 2020; 49:102029 Establishment of three human induced pluripotent stem cell lines from a type 1 diabetic family harboring sequence variants associated with autoimmunity.

Application : ICC/IF

Reactivity : Human

Hsu HS et al. J Biomed Sci 2020; 27 (1):5 Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells.

Blanas A et al. Cancers (Basel) 2020; 12 (9) FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.

Application : ICC/IF, FACS

Reactivity : Mouse

Zhang G et al. Cancer Sci 2020; 111 (11):4166-4176 RBPJ contributes to the malignancy of glioblastoma and induction of proneural-mesenchymal transition via IL-6-STAT3 pathway.

Application : WB

Reactivity : Human

Chi HC et al. Oncogene 2020; 39 (37):5933-5949 DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits.

Application : WB

Reactivity : Human

Wang J et al. Front Cell Neurosci 2020; 14:581861 The Effect of IDO on Neural Progenitor Cell Survival Under Oxygen Glucose Deprivation.

Application : ICC/IF

Reactivity : Human

Kerschner JL et al. J Cell Mol Med 2020; A functional genomics approach to investigate the differentiation of iPSCs into lung epithelium at air-liquid interface.

Reactivity : Human

Chiou HC et al. Neoplasia 2020; 22 (7):263-271 Stemness regulation of the adrenal mixed corticomedullary tumorigenesis-a case-control study.

Application : IHC-P

Reactivity : Human

Wang IH et al. Cancers (Basel) 2020; 12 (5) Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression.

Application : WB

Reactivity : Human

He X et al. Stem Cell Res Ther 2020; 11 (1):157 Characterisation of extraembryonic endoderm-like cells from mouse embryonic fibroblasts induced using chemicals alone.

Application : ICC/IF

Reactivity : Mouse

Zhao T et al. Stem Cell Reports 2020; 14 (3):493-505 lncRNA 5430416N02Rik Promotes the Proliferation of Mouse Embryonic Stem Cells by Activating Mid1 Expression through 3D Chromatin Architecture.

Application : WB

Reactivity : Mouse

Wang CH et al. Sci Rep 2020; 10 (1):2187 The novel application of cordycepin in maintaining stem cell pluripotency and increasing iPS cell generation efficiency.

Application : WB

Reactivity : Mouse

Li X et al. J Cancer 2020; 11 (9):2560-2571 Function of BMP4 in the Formation of Vasculogenic Mimicry in Hepatocellular Carcinoma.

Application : WB

Reactivity : Human

Chen YL et al. Cancers (Basel) 2019; 12 (1) ERK Activation Modulates Cancer Stemness and Motility of a Novel Mouse Oral Squamous Cell Carcinoma Cell Line.

Yang SC et al. FASEB J 2019; 33 (9):10577-10592 Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2.

Fletcher PA et al. Front Endocrinol (Lausanne) 2019; 10:623 Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells.

Application : ICC/IF

Reactivity : Rat

Chang WF et al. Int J Mol Sci 2019; 20 (5) Compromised Chondrocyte Differentiation Capacity in TERC Knockout Mouse Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer.

Chien CH et al. J Biomed Sci 2019; 26 (1):77 Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets.

Application : WB

Reactivity : Human

Bayat Mokhtari R et al. BMC Cancer 2019; 19 (1):864 Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane.

Application : ICC/IF

Reactivity : Human

Chen YH et al. Sci Rep 2019; 9 (1):9919 Mitochondrial Akt Signaling Modulated Reprogramming of Somatic Cells.

Application : ICC/IF

Reactivity : Human

Wang L et al. Toxicol Appl Pharmacol 2019; 376:9-16 Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase.

Application : WB

Reactivity : Rat

Yang Y et al. Neurochem Res 2019; 44 (4):811-828 MiR-124 Enriched Exosomes Promoted the M2 Polarization of Microglia and Enhanced Hippocampus Neurogenesis After Traumatic Brain Injury by Inhibiting TLR4 Pathway.

Application : IHC-P

Reactivity : Rat

Mansel C et al. Neurotoxicol Teratol 2019; 72:58-70 Lead exposure reduces survival, neuronal determination, and differentiation of P19 stem cells.

Application : ICC/IF

Reactivity : Mouse

Zhong PQ et al. Cell Signal 2019; 53:390-399 ACTL6A interacts with p53 in acute promyelocytic leukemia cell lines to affect differentiation via the Sox2/Notch1 signaling pathway.

Application : WB

Reactivity : Human

Hildebrandt TB et al. Nat Commun 2018; 9 (1):2589 Embryos and embryonic stem cells from the white rhinoceros.

Application : ICC/IF

Reactivity : Mouse

Fawal MA et al. Cell Rep 2018; 23 (10):2864-2873.e7 Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation.

Application : ICC/IF

Reactivity : Mouse

Shen Z et al. Elife 2017; 6 Enforcement of developmental lineage specificity by transcription factor Oct1.

Yoshimura A et al. Dis Model Mech 2017; (Epub) The Sox2 promoter-driven CD63-GFP transgenic rat model allows tracking neural stem cell-derived extracellular vesicles.

Application : IHC-Fr

Ko CY et al. Mol Neurobiol 2017; (Epub) MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.

Application : WB

Reactivity : Human

Lin HC et al. J Agric Food Chem 2017; 65 (1):51-59 Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets.

Application : WB

Reactivity : Human

Gong W et al. Am J Cancer Res 2017; 7 (3):503-517 Nodal signaling activates the Smad2/3 pathway to regulate stem cell-like properties in breast cancer cells.

Application : WB

Reactivity : Human

Chen MW et al. Cancer Res 2017; The STAT3-miRNA-92-Wnt signaling pathway regulates spheroid formation and malignant progression in ovarian cancer.

Gazarian KG et al. PLoS One 2017; 12 (1):e0170321 Human Deciduous Teeth Stem Cells (SHED) Display Neural Crest Signature Characters.

Application : ICC/IF

Reactivity : Human

Ye Y et al. Neural Plast 2016; 2016:8072156 Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway.

Hsu CC et al. J Biomed Sci 2016; 23 (1):81 Suberoylanilide hydroxamic acid represses glioma stem-like cells.

Ye Y et al. Neural Plasticity 2016; (Epub) Activation of sphingosine 1-phosphate receptor 1 enhances hippocampus neurogenesis in a rat model of traumatic brain injury: an involvement of MEK/Erk signaling pathway.

Application : IHC-P

Reactivity : Rat

Chang WF et al. PLoS One 2016; 11 (11):e0165715 Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells.

Application : ICC/IF

Reactivity : Human

Chen MJ et al. Sci Rep 2016; 6:34933 PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via β-catenin-mediated stemness.

Application : WB

Reactivity : Human

Petrova A et al. Stem Cells Dev 2016; 25 (18):1366-75 Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin.

Application : ICC/IF

Reactivity : Human

Zhang W et al. Sci Rep 2016; 6:26804 Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription.

Application : WB

Reactivity : Human

Chen CH et al. Anim Biotechnol 2016; 27 (3):157-65 Germline Competent Pluripotent Mouse Stem Cells Generated by Plasmid Vectors.

Application : ICC/IF

Reactivity : Human

Zhao T et al. PLoS One 2015; 10 (9):e0138168 Roles of Klf5 Acetylation in the Self-Renewal and the Differentiation of Mouse Embryonic Stem Cells.

Application : WB

Reactivity : Mouse

Mineda K et al. Stem Cells Transl Med 2015; 4 (12):1511-22 Therapeutic Potential of Human Adipose-Derived Stem/Stromal Cell Microspheroids Prepared by Three-Dimensional Culture in Non-Cross-Linked Hyaluronic Acid Gel.

Application : IHC-Fr

Reactivity : Human

Chen H et al. Proc Natl Acad Sci U S A 2015; 112 (44):E5936-43 Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells.

Application : WB

Reactivity : Mouse

Wang AM et al. Oncotarget 2014; 5 (13):5002-16 Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesis.

Application : WB

Reactivity : Human

Hung YH et al. Mol Neurobiol 2014; Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons.

Application : WB

Reactivity : Rat

Emhemmed F et al. Biochem Pharmacol 2014; Selective anticancer effects of a synthetic flavagline on human Oct4-expressing cancer stem-like cells via a p38 MAPK-dependent caspase-3-dependent pathway.

Application : WB

Reactivity : Human

Misuno K et al. Stem Cell Res Ther 2013; 4 (6):156 Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells.

Application : WB

Reactivity : Human

SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf

Package	List Price ($)
100 μl	$ 399
25 μl	$ 169
Qty

SOX2 antibody [N1C3]

Cat. No. GTX101507

Host

Clonality

Isotype

Application

Reactivity

Summary

APPLICATION

Application Note

Calculated MW

Positive Control

Predict Reactivity

PROPERTIES

Form

Buffer

Preservative

Storage

Concentration

Antigen Species

Immunogen

Purification

Conjugation

RRID

Note

TARGET

Synonyms

Cellular Localization

Background

Database

Research Area

DATA IMAGES

GTX101507 WB Image

GTX101507 IHC-P Image

GTX101507 WB Image

GTX101507 WB Image

GTX101507 ICC/IF Image

GTX101507 IHC-Fr Image

GTX101507 IHC-Fr Image

GTX101507 ICC/IF Image

GTX101507 FACS Image

GTX101507 IHC-P Image

GTX101507 WB Image

GTX101507 IHC-P Image

GTX101507 WB Image

GTX101507 IHC-P Image

GTX101507 IP Image

GTX101507 IP Image

GTX101507 WB Image

GTX101507 IHC-Fr Image

GTX101507 ICC/IF Image

GTX101507 IHC-P Image

GTX101507 IHC-P Image

GTX101507 IHC-P Image

GTX101507 WB Image

GTX101507 WB Image

GTX101507 ICC/IF Image

GTX101507 WB Image

GTX101507 IHC-P Image

GTX101507 IHC-P Image

GTX101507 WB Image

GTX101507 IHC-Fr Image

GTX101507 ICC/IF Image

GTX101507 WB Image

GTX101507 ICC/IF Image

REFERENCE

Application Reference

REVIEW

SOX2 antibody [N1C3] Cat. No. GTX101507

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Research

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