APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1-3 μg/mL |
| 10 μg/ml/ml |
| ≤1:32000 |
Not tested in other applications.
Calculated MW
Positive Control
The peptide used to generate this antibody is available for purchase (GTX31103-PEP).
Predict Reactivity
Mouse, Rat(>80% identity)
PROPERTIES
Form
Liquid
Buffer
TBS, 0.5% BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide with sequence C-LHQGERETWGK, from the internal region of the protein sequence according to NP_001036.1.
Purification
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
solute carrier family 6 member 4 , 5-HTT , 5-HTTLPR , 5HTT , HTT , OCD1 , SERT , SERT1 , hSERT
Cellular Localization
Cell membrane , Endosome membrane
Background
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31103 WB Image
WB analysis of human colon lysate using GTX31103 Serotonin Transporter antibody, Internal.
Dilution : 2μg/ml
Loading : 35μg protein in RIPA buffer
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GTX31103 ICC/IF Image
ICC/IF analysis of PFA-fixed HepG2 cells using using GTX31103 Serotonin Transporter antibody, Internal.
Green : Primary antibody
Blue : DAPI
Negative control: Unimmunized goat IgG
Permeabilization : 0.15% Triton
Dilution : 10 μg/mL
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REFERENCE
There are currently no references for Serotonin Transporter antibody, Internal (GTX31103). Be the first to share your publications with this product.
REVIEW
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