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Somatostatin antibody [YC7]

Cat. No. GTX39061

Reference 4

Host

 Rat

Clonality

 Monoclonal

Clone Name

 YC7

Isotype

 IgG2b

Application

 ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat, Zebrafish, Guinea pig, Pig
Package
200 μl ($529)
See all Somatostatin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

13 kDa. ( Note )

Product Note

The epitope recognised by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.05% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Somatostatin conjugated to thyroglobulin.

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

RRID

AB_11166120

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

somatostatin , SMST

Cellular Localization

Secreted

Background

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Mi J et al. Sci Adv 2023; 9 (33) : eadf5142 Decoding pancreatic endocrine cell differentiation and β cell regeneration in zebrafish.
Ghoneim MA et al. Stem Cell Res Ther 2022; 13 (1) : 350 Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice.
Application : IHC-P
Reactivity : Mouse
Zhang W et al. Biochem Biophys Res Commun 2017; (Epub) neuromedin u suppresses glucose-stimulated * secretion in pancreatic β cells.
Application : ICC/IF
Reactivity : Mouse
Masjkur J et al. J Biol Chem 2014; hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and * release.
Application : IHC-Fr
Reactivity : Mouse
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Package List Price ($)
$ 529