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gamma Sarcoglycan antibody [35DAG/21B5]

Cat. No. GTX01944

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 35DAG/21B5

Isotype

 IgG2b

Application

 IHC-Fr

Reactivity

 Human, Rabbit
Package
500 μl ($669)
See all gamma Sarcoglycan products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1:100

Note :

IHC-Fr
Freeze specimen tissue blocks in isopentane chilled in liquid nitrogen.
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Rabbit

Immunogen

Synthetic peptide containing amino acids 167–178 of the rabbit gamma-sarcoglycan sequence (Noguchi et al., 1995).

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sarcoglycan gamma , 35DAG , A4 , DAGA4 , DMDA , DMDA1 , LGMD2C , LGMDR5 , MAM , SCARMD2 , SCG3 , gamma-SG

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 669