Cancer Tissue Gallery- GTX640556

53BP1 antibody [HMV324] HistoMAXTM

 

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Adrenal gland – Adrenocortical adenoma with strong 53BP1 immunostaining of tumor cells

Adrenal gland – Pheochromocytoma with strong 53BP1 positivity of all tumor cells

Breast – Invasive breast cancer of no special type (NST) with strong 53BP1 staining ofall tumor cells

Breast – Invasive lobular breast cancer with strong 53BP1 immunostaining of tumor cells

       

Esophagus – Adenocarcinoma with distinct 53BP1 staining of 100_ of tumor cells

Esophagus – Squamous cell carcinoma with distinct 53BP1 staining of cancer cells

Kidney – Clear cell renal cell carcinoma with distinct 53BP1 positivity of tumor cells

Kidney – Papillary renal cell carcinoma with strong 53BP1 immunostaining of tumor cells

       

Liver – Cholangiocellular carcinoma with strong 53BP1 immunostaining of tumor cells

Liver – Hepatocellular carcinoma with a variable (mostly weak) 53BP1 staining of tumor cells

Lymph node – Diffuse large B-cell lymphoma with strong 53BP1 staining of tumor cells

Oral cavity – Squamous cell carcinoma exhibiting a strong 53BP1 staining of cancer cells

       

Ovary – Endometroid carcinoma displaying a strong 53BP1 staining of all tumor cells

Ovary – Serous high-grade carcinoma with strong 53BP1 immunostaining of all cells

Pancreas – Ductal adenocarcinoma showing an intense 53BP1 staining of tumor cells

Pancreas – Neuroendocrine tumor with strong 53BP1 staining of tumor cells

       

Prostate – Adenocarcinoma (Gleason 3+3=6) with distinct 53BP1 staining of tumor cells

Prostate – Adenocarcinoma (Gleason 4+4=8) with strong 53BP1 positivity of cancer cells

Prostate – Adenocarcinoma (Gleason 5+5=10) with intense 53BP1 staining of tumor cells

Salivary gland – Warthin tumor with strong 53BP1 staining of tumor cells. Staining is less intense in tumor-associated lymphocytes

       

Skin – Malignant melanoma displaying an intense, predominantly nuclear 53BP1 positivity of neoplastic cells

Stomach – Gastric adenocarcinoma displaying an intense 53BP1 staining of all cancer cells

Stomach – Gastrointestinal stromal tumor (GIST) showing a strong 53BP1 staining of tumor cells

Testis – Leydig cell tumor with strong 53BP1 staining of tumor cells

       

Testis – Seminoma with strong 53BP1 staining of tumor cells (markedly stronger than in associated inflammatory cells)

Urinary bladder – Muscle-invasive urothelial carcinoma with intense 53BP1 positivity of tumor cells

Uterus, cervix – Squamous cell carcinoma with strong 53BP1 positivity of tumor cells

     

 

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