Normal Tissue Gallery- GTX639927

Glucocorticoid Receptor antibody [HMV304] HistoMAXTM

 

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Adrenal gland – Moderate to strong GR positivity of medullary cells while adrenocortical cells are largely GR negative

Aorta, media – Moderate to strong GR positivity of spindle shaped cells in the media

Appendix, mucosa – Moderate GR positivity of superficial epithelial cells. Epithelial cell staining decreases markedly towards the base of crypts. GR staining is markedly stronger in lymphocytes

Appendix, mucosa – Moderate GR positivity of epithelial cells. Staining is stronger in lymphocytes

       

Appendix, muscular wall – Moderate to strong GR positivity of smooth muscle cells

Bone marrow – Strong GR positivity of almost all hematopoetic cells

Breast – Moderate to strong GR positivity of myoepithelial and luminal cells

Bronchus, mucosa – Moderate to strong GR positivity of respiratory epithelial cells

       

Cerebellum (white matter)

Cerebellum, cortex (molecular layer, Purkinje cell layer, granule cell layer)

Cerebrum, grey matter – Moderate GR positivity of neuronal cells

Cerebrum, white matter

       

Cerebrum, white matter

colon descendens, mucosa – Moderate GR positivity of epithelial cells

Colon descendens, muscular wall – Moderate to strong GR positivity of smooth muscle cells

Duodenum, Brunner gland – Moderate GR positivity of Brunner gland cells

       

Duodenum, mucosa – Strong GR positivity of superficial epithelial cells. Staining is somewhat weaker in the crypts

Epididymis – Moderate to strong GR positivity of all epithelial cells of the caput epididymis

Esophagus, squamous epithelium – Intense GR staining of squamous epithelial cells. Staining intensity decreases sligthly towards the surface

Fallopian tube, mucosa – Strong GR positivity of all epithelial cells

       

Fat – Strong GR positivity of fat cells

Gallbladder, epithelium – Strong GR positivity of epithelial cells

Heart muscle – Strong GR positivity of heart muscle cells

Ileum, mucosa – Moderate GR positivity of epithelial cells. Staining is stronger in lymphocytes

       

Kidney, cortex – Moderate to strong GR positivity of all epithelial cells

Kidney, medulla – Moderate to strong GR positivity of all epithelial cells

Kidney, pelvis, urothelium – Weak to moderate GR positivity of the basal and suprabasal cell layers of the urohelium. Superficial cell layers are largely GR negative

Liver – Moderate GR positivity of hepatocytes, ductal cells and of lymphocytes

       

Lung – Strong GR positivity of pneumocytes

Lymph node – Strong GR positivity of lymphocytic cells

Ovary, corpus luteum – Moderate to strong GR positivity of corpus luteum cells

Ovary, follicular cyst – Granulosa cells are largely GR negative

       

Ovary, stroma – Strong GR positivity of stromal cells

Pancreas – Moderate to strong GR positivity of acinar cells while islet cells show a strong staining

Parathyroid – Moderate to strong GR positivity of epithelial cells

Pituitary gland, anterior lobe – Moderate to strong GR positivity of epithelial cells

       

Pituitary gland, posterior lobe – Weak GR positivity of pituicytes

Placenta, early – Strong GR staining of trophoblast and stroma cells

Placenta, mature – Strong GR staining of stroma cells while trophoblast cells are negative

Placenta, mature, amnion and chorion – Strong GR positivity of amnion and chorion cells

       

Prostate – Moderate to strong GR positivity of epithelial cells

Rectum, mucosa – Weak to moderate GR positivity of epithelial cells. GR staining is markedly stronger in lymphocytes

Seminal vesicle – Moderate to strong GR positivity of all epithelial cells

Sinus paranasales – Moderate to strong GR positivity of respiratory epithelial cells

       

Skeletal muscle – Strong GR positivity of skeletal muscle cells

Skin – Intense GR positivity of squamous epithelial cells. Staining intensity decreases slightly towards the surface

Spleen – Strong GR positivity of lymphocytic cells

Stomach, antrum – Moderate GR positivity of superficial epithelial cells. Staining is weakest in gastric glands

       

Stomach, corpus – Moderate GR positivity of superficial epithelial cells. Staining is weakest in gastric glands

Submandibular gland – Moderate to strong GR positivity of all epithelial cells

Testis – Intense GR positivity of Sertoli and Leydig cells. Cells of the spermatogenesis do not show significant GR staining

Thymus – Strong GR positivity of lymphocytic cells. GR staining is only weak in squamous epithelial cells of corpuscles of Hassall's

       

Thyroid gland – Moderate to strong GR positivity of follicular epithelial cells

Tonsil – Strong GR positivity of lymphocytic cells

Tonsil, surface epithelium – Intense GR positivity of squamous epithelial cells. Staining intensity decreases slightly towards the surface

Urinary bladder, muscular wall – Moderate GR positivity of smooth muscle cells

       

Urinary bladder, urothelium – Weak to moderate GR positivity of the basal and suprabasal cell layers of the urohelium. Superficial cell layers are largely GR negative

Uterus, ectocervix – Significant GR staining of squamous epithelial cells. Staining intensity decreases sligthly towards the surface

Uterus, endocervix – Moderate GR positivity of epithelial cells

Uterus, endometrium (pregnancy) – Moderate GR positivity of decidua and of epithelial cells

       

Uterus, endometrium (secretion) – Moderate GR positivity of stroma cells while endometrium cells are largely GR negative

Uterus, myometrium – Strong GR positivity of myometrial cells

   

 

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