Adrenal gland – HLA-DRB1 staining in scattered inflammatory cells and in endothelial cells (HLA-DRB1 immunohistochemistry)

Aorta, media

Appendix, mucosa – Strong HLA-DRB1 staining of mucosal inflammatory cells. Superfical epithelial cells also show a weak focal positivity (HLA-DRB1 immunohistochemistry)

Appendix, muscular wall – HLA-DRB1 staining in dispersed inflammatory cells (HLA-DRB1 immunohistochemistry)

Bone marrow – HLA-DRB1 staining of few scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Breast – HLA-DRB1 staining in scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Bronchus, glands – Strong membranous HLA-DRB1 staining in a group of glandular epithelial cells (HLA-DRB1 immunohistochemistry)

Bronchus, mucosa – HLA-DRB1 staining in scattered inflammatory cells while epithelial cells are unstained in this sample (HLA-DRB1 immunohistochemistry)

Bronchus, mucosa – Significant HLA-DRB1 staining of epithelial cells in this sample (HLA-DRB1 immunohistochemistry)

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)

Cerebellum, grey (Stratum neuronorum)

Cerebrum, grey matter

Cerebrum, white matter

Colon descendens, mucosa – Strong HLA-DRB1 staining of mucosal inflammatory cells (HLA-DRB1 immunohistochemistry)

Colon descendens, muscular wall – HLA-DRB1 staining in dispersed inflammatory cells (HLA-DRB1 immunohistochemistry)

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, mucosa – Intense HLA-DRB1 staining of macrophages and possibly other inflammatory cells. Superfical epithelial cells also exhibit a positive staining (HLA-DRB1 immunohistochemistry)

Epididymis – HLA-DRB1 staining in scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Esophagus, squamous epithelium – HLA-DRB1 staining of scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Fallopian tube, mucosa – HLA-DRB1 staining in a fraction of epithelial cells and in few inflammatory cells in this sample (HLA-DRB1 immunohistochemistry)

Fallopian tube, mucosa – HLA-DRB1 staining in restricted to few inflammatory cells in this sample (HLA-DRB1 immunohistochemistry)

Fat

Gallbladder, epithelium – HLA-DRB1 staining of scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Heart muscle

Ileum, mucosa – Intense HLA-DRB1 staining of macrophages and possibly other inflammatory cells. Superfical epithelial cells also exhibit a positive staining (HLA-DRB1 immunohistochemistry)

Kidney, cortex – HLA-DRB1 staining is limited to endothelial cells including glomerular endothelium in the non-inflamed kidney (HLA-DRB1 immunohistochemistry)

Kidney, cortex – In the inflamed kidney, HLA-DRB1 staining is seen in endothelial cells, inflammatory cells and in tubulus cells adjacent to inflammation (HLA-DRB1 immunohistochemistry)

Kidney, medulla – HLA-DRB1 staining is largely lacking in this sample (HLA-DRB1 immunohistochemistry)

Kidney, medulla – Intense HLA-DRB1 staining in all endothelial cells in this sample (HLA-DRB1 immunohistochemistry)

Kidney, medulla – Intense HLA-DRB1 staining in endothelial cells in this sample (HLA-DRB1 immunohistochemistry)

Liver – Intense HLA-DRB1 staining of inflammatory cells and of Kupffer cells (HLA-DRB1 immunohistochemistry)

Lung – Strong HLA-DRB1 staining in alveolar macrophages (HLA-DRB1 immunohistochemistry)

Lymph node – HLA-DRB1 staining macrophages, dendritic cells and B-lymphocytes. Some endothelial cells also stain positive (HLA-DRB1 immunohistochemistry)

Ovary, stroma

Pancreas – Distinct HLA-DRB1 positivity of inflammatory cells and endothelial cells of small capillaries (HLA-DRB1 immunohistochemistry)

Pancreas – Strong HLA-DRB1 staining of inflammatory cells. Few acinar epithelial cells also show a weak focal positivity (HLA-DRB1 immunohistochemistry)

Parathyroid gland

Parotid gland – Distinct HLA-DRB1 staining of few epithelial cells. Some scattered inflammatory cells are also positive (HLA-DRB1 immunohistochemistry)

Pituitary gland, anterior lobe – Significant HLA-DRB1 staining in endothelial cells (HLA-DRB1 immunohistochemistry)

Pituitary gland, posterior lobe

Placenta (amnion and chorion) – HLA-DRB1 staining of scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Placenta (amnion and chorion)

Placenta, early

Placenta, mature

Prostate – HLA-DRB1 staining in scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Rectum, mucosa

Seminal vesicle – HLA-DRB1 staining in scattered inflammatory cells and in some endothelial cells of small capillaries (HLA-DRB1 immunohistochemistry)

Sinus paranasales – HLA-DRB1 staining in scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Skeletal muscle

Skin – HLA-DRB1 staining of scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Spleen – HLA-DRB1 staining of lymphocytes and macrophages (HLA-DRB1 immunohistochemistry)

Stomach, antrum

Stomach, corpus – HLA-DRB1 staining of scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Sublingual gland – HLA-DRB1 staining is largely limited to endothelial cells and few inflammatory cells in this sample (HLA-DRB1 immunohistochemistry)

Sublingual gland – Intense HLA-DRB1 staining in most epithelial cells. Endothelium and some discernible inflammatory cells are also positive in this sample (HLA-DRB1 immunohistochemistry)

Testis

Thymus – HLA-DRB1 staining of a subset of cells. Most thymocytes remain negative (HLA-DRB1 immunohistochemistry)

Thyroid gland

Tonsil – HLA-DRB1 staining of a large fraction of lymphocytes (HLA-DRB1 immunohistochemistry)

Tonsil, surface epithelium – HLA-DRB1 staining of some inflammatory cells, mainly macrophages and B-lymphocytes (HLA-DRB1 immunohistochemistry)

Urinary bladder, muscular wall

Urinary bladder, muscular wall (2)

Urinary bladder, urothelium – HLA-DRB1 staining of scattered inflammatory cells and of endothelial cells in blood vessels (HLA-DRB1 immunohistochemistry)

Uterus, ectocervix – HLA-DRB1 staining of scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Uterus, endocervix – HLA-DRB1 staining in scattered inflammatory cells, endothelial cells and in some epithelial cells (HLA-DRB1 immunohistochemistry)

Uterus, endometrium (pregnancy) – Strong HLA-DRB1 staining in scattered inflammatory cells (HLA-DRB1 immunohistochemistry)

Uterus, endometrium (proliferation) – HLA-DRB1 staining in scattered inflammatory cells and – focally – in some epithelial cells (HLA-DRB1 immunohistochemistry)

Uterus, endometrium (secretion) – HLA-DRB1 staining in scattered inflammatory cells and in endothelial cells (HLA-DRB1 immunohistochemistry)

Uterus, myometrium