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HMGB1 antibody [HMV317] HistoMAX™

Recombinant antibody HistoMAX
Anti-HMGB1 antibody [HMV317] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639941
Anti-HMGB1 antibody [HMV317] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639941
Anti-HMGB1 antibody [HMV317] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639941

Cat. No. GTX639941

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HMV317

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649),
100 μl ($329)
See all HMGB1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HMGB1. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

high mobility group box 1,HMG-1,HMG1,HMG3,SBP-1

Cellular Localization

Nucleus,Cytoplasm,Secreted,Cell membrane,Endosome

Background

This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-HMGB1 antibody [HMV317] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639941

GTX639941 IHC-P Image

IHC-P analysis of human Placenta (amnion and chorion) tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX™.
Strong nuclear HMGB1 staining of chorion cells, moderate nuclear HMGB1 staining of amnion cells.

Anti-HMGB1 antibody [HMV317] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639941

GTX639941 IHC-P Image

IHC-P analysis of human Esophagus tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX™.
Squamous cell carcinoma with strong HMGB1 staining of tumor cells.

Anti-HMGB1 antibody [HMV317] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639941

GTX639941 IHC-P Image

IHC-P analysis of human Soft tissue using GTX639941 HMGB1 antibody [HMV317] HistoMAX™.
Primitive neuroektodermal tumor (PNET) showing intense HMGB1 staining of tumor cells

REFERENCE

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REVIEW

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Package List Price ($)
$ 649
$ 329