GeneTex

  • Country / Location Selection

United States (US)

Mre11 antibody [HMV328] HistoMAX™

Recombinant antibody HistoMAX
Anti-Mre11 antibody [HMV328] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX640560
Anti-Mre11 antibody [HMV328] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX640560
Anti-Mre11 antibody [HMV328] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX640560

Cat. No. GTX640560

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HMV328

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649),
100 μl ($329)
See all Mre11 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Mre11. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MRE11 homolog,double strand break repair nuclease,ATLD,HNGS1,MRE11A,MRE11B

Cellular Localization

Nucleus

Background

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Mre11 antibody [HMV328] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX640560

GTX640560 IHC-P Image

IHC-P analysis of human stomach tissue using GTX640560 Mre11 antibody [HMV328] HistoMAX™.
Gastric adenocarcinoma (intestinal type) exhibiting only a weak nuclear MRE11 staining of tumor cells.

Anti-Mre11 antibody [HMV328] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX640560

GTX640560 IHC-P Image

IHC-P analysis of human stomach tissue using GTX640560 Mre11 antibody [HMV328] HistoMAX™.
Gastric adenocarcinoma (diffuse type) with strong nuclear MRE11 positivity of all tumor cells.

Anti-Mre11 antibody [HMV328] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX640560

GTX640560 IHC-P Image

IHC-P analysis of human stomach tissue using GTX640560 Mre11 antibody [HMV328] HistoMAX™.
Gastrointestinal stromal tumor (GIST) with prominent nuclear MRE11 staining of tumor cells.

REFERENCE

There are currently no references for Mre11 antibody [HMV328] HistoMAX™ (GTX640560). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Mre11 antibody [HMV328] HistoMAX™ (GTX640560). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 649
$ 329
Available soon.