APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100-1:200 |
Not tested in other applications.
PROPERTIES
Form
Liquid
Buffer
PBS, 2% BSA
Preservative
0.025% ProClin 300
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.22 mg/ml
Antigen Species
Human
Immunogen
Recombinant fragment of human SDHB.
Purification
Affinity purified by Protein A.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
succinate dehydrogenase complex iron sulfur subunit B,CWS2,IP,PGL4,SDH,SDH1,SDH2,SDHIP
Background
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX639944 IHC-P Image
IHC-P analysis of human salivary gland tissue using GTX639944 SDHB antibody [HMV320] HistoMAX™. Warthin tumor with intensive SDHB immunostaining of epithelial tumor cells.
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GTX639944 IHC-P Image
IHC-P analysis of human adrenal gland tissue using GTX639944 SDHB antibody [HMV320] HistoMAX™. Adrenocortical carcinoma with intense SDHB staining of all tumor cells.
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GTX639944 IHC-P Image
IHC-P analysis of human liver tissue using GTX639944 SDHB antibody [HMV320] HistoMAX™. Substantial granular cytoplasmic SDHB staining of cells, especially in hepatocytes.
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REFERENCE
There are currently no references for SDHB antibody [HMV320] HistoMAX™ (GTX639944). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for SDHB antibody [HMV320] HistoMAX™ (GTX639944). Be the first to share your experience with this product.